Synthesis, anticancer evaluation and molecular docking studies of new benzimidazole-1, 3, 4-oxadiazole derivatives as human topoisomerase types I poison
In this study, some benzimidazole-oxadiazole derivatives were synthesised and tested for
their in vitro anticancer activities on five cancer cell lines, including HeLa, MCF7, A549 …
their in vitro anticancer activities on five cancer cell lines, including HeLa, MCF7, A549 …
Type IA topoisomerases as targets for infectious disease treatments
Infectious diseases are one of the main causes of death all over the world, with antimicrobial
resistance presenting a great challenge. New antibiotics need to be developed to provide …
resistance presenting a great challenge. New antibiotics need to be developed to provide …
Polydispersity-mediated high efficacy of an in-situ aqueous nanosuspension of PPEF. 3HCl in methicillin resistant Staphylococcus aureus sepsis model
AS Lokhande, V Maurya, K Rani, P Parashar… - International Journal of …, 2024 - Elsevier
Abstract Recently, World Health Organization declared antimicrobial resistance as the third
greatest threat to human health. Absence of known cross-resistance, new class, new target …
greatest threat to human health. Absence of known cross-resistance, new class, new target …
Unraveling topoisomerase IA gate dynamics in presence of PPEF and its preclinical evaluation against multidrug-resistant pathogens
Type IA topoisomerases maintain DNA topology by cleaving ssDNA and relaxing negative
supercoils. The inhibition of its activity in bacteria prevents the relaxation of negative …
supercoils. The inhibition of its activity in bacteria prevents the relaxation of negative …
Antimicrobial properties of heterojunction BiSnSbO6-ZnO composites in wastewater treatment
J Chen, M Shan, H Zhu, S Zhang, J Li, L Li - Environmental Science and …, 2023 - Springer
BiSnSbO6-ZnO composite photocatalytic material with type II heterojunction structure was
synthesized by a simple solid-phase sintering method, it was characterized by XRD, UV–vis …
synthesized by a simple solid-phase sintering method, it was characterized by XRD, UV–vis …
Synthesis and Biological Evaluation of Novel 1H-Benzo[d]imidazole Derivatives as Potential Anticancer Agents Targeting Human Topoisomerase I
S Pandey, P Tripathi, P Parashar, V Maurya… - ACS …, 2022 - ACS Publications
Small molecules that modulate biological functions are targets of modern-day drug
discovery efforts. A new series of novel 1 H-benzo [d] imidazoles (BBZs) were designed and …
discovery efforts. A new series of novel 1 H-benzo [d] imidazoles (BBZs) were designed and …
[PDF][PDF] Type IA Topoisomerases as Targets for Infectious Disease Treatments. Microorganisms 2021, 9, 86
A Seddek, T Annamalai, YC Tse-Dinh - 2021 - pdfs.semanticscholar.org
Infectious diseases are one of the main causes of death all over the world, with antimicrobial
resistance presenting a great challenge. New antibiotics need to be developed to provide …
resistance presenting a great challenge. New antibiotics need to be developed to provide …