Mechanisms of esophageal protection, gastroprotection and ulcer healing by melatonin. implications for the therapeutic use of melatonin in gastroesophageal reflux …

I Brzozowska, M Strzalka, D Drozdowicz… - Current …, 2014 - benthamdirect.com
Melatonin is a potent reactive oxygen metabolite scavenger and antioxidant that has been
shown to influence many physiological functions of the gastrointestinal (GI) tract including …

Critical evaluation of animal models of gastrointestinal disorders

AC Johnson, B Greenwood-Van Meerveld - Gastrointestinal …, 2017 - Springer
Preclinical research remains an important tool for discovery and validation of novel
therapeutics for gastrointestinal disorders. While in vitro assays can be used to verify …

Pentadecapeptide BPC 157 and the esophagocutaneous fistula healing therapy

V Cesarec, T Becejac, M Misic, Z Djakovic… - European journal of …, 2013 - Elsevier
Esophagocutaneous fistulas are a failure of the NO-system, due to NO-synthase blockage
by the NOS-blocker L-NAME consequently counteracted by l-arginine and gastric …

Melatonin protects against ischemic heart failure in rats

AÖ Şehirli, D Koyun, Ş Tetik, D Özsavcı… - Journal of pineal …, 2013 - Wiley Online Library
Ischemic injury, which occurs as a result of sympathetic hyperactivity, plays an important role
in heart failure. Melatonin is thought to have antiatherogenic, antioxidant, and vasodilatory …

Melatonin attenuates expression of cyclooxygenase-2 (COX-2) in activated microglia induced by lipopolysaccharide (LPS)

C Yao, X Liu, Z Zhou, Y Xiang, S Yuan… - Journal of Toxicology …, 2019 - Taylor & Francis
Lipopolysaccharide (LPS) is a known neurotoxin and utilized most extensively as a
microglial activator for induction of inflammatory neurodegeneration. Melatonin (MEL) is the …

[HTML][HTML] Berberine protects against esophageal mucosal damage in reflux esophagitis by suppressing proinflammatory cytokines

BK Choo, SS Roh - Experimental and Therapeutic …, 2013 - spandidos-publications.com
This study was performed to investigate the effects of berberine (BB) in a rat model of
gastroesophageal reflux disease (GERD), induced by pylorus and forestomach ligation. We …

Esophagoprotection mediated by exogenous and endogenous melatonin in an experimental model of reflux esophagitis

PC Konturek, I Brzozowska, A Targosz… - Journal of pineal …, 2013 - Wiley Online Library
Reflux esophagitis is a common clinical entity in western countries with approximately 30%
of the population experiencing the symptoms at least once every month. The imbalance …

Melatonin, Gastrointestinal Protection, and Oxidative Stress

NT de Talamoni, V Areco, V Rodríguez… - Gastrointestinal …, 2017 - Elsevier
We have tried to summarize the actions of melatonin (MEL) in different organs of the
gastrointestinal tract (GIT) and the potential usefulness as a drug to ameliorate or cure a …

Effectiveness of Vitamin C Solution in Reducing Adverse Reactions Caused by Painless Lugol Chromoendoscopy: A Multicenter Randomized Controlled Trial

X Nie, J Ding, Y He, C Ren, H Lin, C Fan… - Journal of Clinical …, 2022 - journals.lww.com
Background: Lugol chromoendoscopy is an effective method for screening superficial
esophageal squamous cell carcinoma, although Lugol iodine solution (LIS) causes mucosal …

[PDF][PDF] Melatonins effekt på orale inflammasjoner og beintilheling

S Milovanovic - 2021 - duo.uio.no
Melatonin, N-acetyl-5-methoxytryptamine, er navnet på det de fleste forbinder med
søvnhormonet (3). Den største produksjonen av stoffet foregår i epifysen (pinealkjertelen) på …