Relationships between gastric emptying, postprandial glycemia, and incretin hormones

CS Marathe, CK Rayner, KL Jones, M Horowitz - Diabetes care, 2013 - Am Diabetes Assoc
The importance of achieving tight glycemic control, usually assessed by glycated
hemoglobin (HbA1c), for both the prevention and delay in the progression of diabetes …

Liraglutide in type 2 diabetes mellitus: clinical pharmacokinetics and pharmacodynamics

LV Jacobsen, A Flint, AK Olsen, SH Ingwersen - Clinical pharmacokinetics, 2016 - Springer
Liraglutide is an acylated glucagon-like peptide-1 analogue with 97% amino acid homology
with native glucagon-like peptide-1 and greatly protracted action. It is widely used for the …

[HTML][HTML] Personalized nutrition by prediction of glycemic responses

D Zeevi, T Korem, N Zmora, D Israeli, D Rothschild… - Cell, 2015 - cell.com
Elevated postprandial blood glucose levels constitute a global epidemic and a major risk
factor for prediabetes and type II diabetes, but existing dietary methods for controlling them …

Effects of liraglutide on weight, satiation, and gastric functions in obesity: a randomised, placebo-controlled pilot trial

H Halawi, D Khemani, D Eckert, J O'Neill… - The Lancet …, 2017 - thelancet.com
Background Liraglutide, a long-acting GLP-1 receptor agonist, is approved for treatment of
obesity; however, the mechanisms of action of liraglutide are incompletely understood. We …

Effects of fat on gastric emptying of and the glycemic, insulin, and incretin responses to a carbohydrate meal in type 2 diabetes

D Gentilcore, R Chaikomin, KL Jones… - The Journal of …, 2006 - academic.oup.com
Context: Gastric emptying (GE) is a major determinant of postprandial glycemia. Because
the presence of fat in the small intestine inhibits GE, ingestion of fat may attenuate the …

Dietary compensation by humans for supplemental energy provided as ethanol or carbohydrate in fluids

RD Mattes - Physiology & behavior, 1996 - Elsevier
Dietary compensation for energy provided as ethanol is reportedly limited. Whether this is a
function of the ethanol or other aspect of the medium in which it is ingested is not known …

[图书][B] Physiological pharmaceutics: barriers to drug absorption

N Washington, C Washington, C Wilson - 2000 - taylorfrancis.com
In recent years, the emphasis in drug development has been the design of new delivery
systems rather than new drugs. It is the aim of innovative pharmaceutical scientists to design …

Gastric emptying in diabetes: clinical significance and treatment

M Horowitz, D O'donovan, KL Jones, C Feinle… - Diabetic …, 2002 - Wiley Online Library
The outcome of recent studies has led to redefinition of concepts relating to the prevalence,
pathogenesis and clinical significance of disordered gastric emptying in patients with …

Gastrointestinal targets of appetite regulation in humans

N Delzenne, J Blundell, F Brouns… - Obesity …, 2010 - Wiley Online Library
The aim of this paper is to describe and discuss relevant aspects of the assessment of
physiological functions–and related biomarkers–implicated in the regulation of appetite in …

Effects of oat bran, rice bran, wheat fiber, and wheat germ on postprandial lipemia in healthy adults

L Cara, C Dubois, P Borel, M Armand, M Senft… - The American journal of …, 1992 - Elsevier
Six normolipidemic males ingested on separate days a low-fiber test meal [2.8 g dietary fiber
(TDF)] containing 70 g fat and 756 mg cholesterol, enriched or not with 10 g TDF as oat …