Deoxynivalenol: emerging toxic mechanisms and control strategies, current and future perspectives

Y Deng, L You, X Wang, W Wu, K Kuca… - Journal of agricultural …, 2023 - ACS Publications
Deoxynivalenol (DON) is the most frequently present mycotoxin contaminant in food and
feed, causing a variety of toxic effects in humans and animals. Currently, a series of …

Detoxification of selenium yeast on mycotoxins and heavy metals: a review

H Sun, J Chen, D Xiong, M Long - Biological Trace Element Research, 2023 - Springer
Mycotoxins are secondary metabolites produced by specific fungi. More than 400 different
mycotoxins are known in the world, and the concentration of these toxins in food and feed …

Mycotoxins: Emerging toxic mechanisms, and unanswered research questions

Q Wu, L You, W Wu, M Long, K Kuca - Food and Chemical Toxicology, 2023 - Elsevier
Recently, a series of toxic mechanisms have been explored in mycotoxins. Emerging
evidence show that mycotoxins may induce human neurodegenerative diseases (ND); …

Quercetin ameliorates ochratoxin A-Induced immunotoxicity in broiler chickens by modulation of PI3K/AKT pathway

RE Abdelrahman, AAA Khalaf, MA Elhady… - Chemico-biological …, 2022 - Elsevier
Ochratoxin A (OTA) is a fungal secondary metabolite produced by certain species of
Aspergillus and Penicillium, and exerts immunosuppressive effect on humans and animals …

DNA walker-assisted aptasensor for highly sensitive determination of Ochratoxin A

Y Wang, W Song, H Zhao, X Ma, S Yang, X Qiao… - Biosensors and …, 2021 - Elsevier
Ochratoxin A (OTA), a toxic secondary metabolite produced via various fungus, poses a
serious threat to the health of human beings and animals. In this paper, an aptasensor for …

Selenium yeast alleviates ochratoxin A-induced hepatotoxicity via modulation of the PI3K/AKT and Nrf2/Keap1 signaling pathways in chickens

P Li, K Li, C Zou, C Tong, L Sun, Z Cao, S Yang, Q Lyu - Toxins, 2020 - mdpi.com
The aim of this study was to investigate the protective effects of selenium yeast (Se-Y)
against hepatotoxicity induced by ochratoxin A (OTA). The OTA-induced liver injury model …

Sustainable and efficient method utilizing N-acetyl-L-cysteine for complete and enhanced ochratoxin A clearance by antagonistic yeast

M Wei, S Dhanasekaran, Q Ji, Q Yang… - Journal of Hazardous …, 2023 - Elsevier
With the increasing global climate change, ochratoxin A (OTA) pollution in food and
environment has become a serious and potential risk element threatening food safety and …

Selenium Yeast Alleviates Ochratoxin A‐Induced Apoptosis and Oxidative Stress via Modulation of the PI3K/AKT and Nrf2/Keap1 Signaling Pathways in the Kidneys …

K Li, Z Cao, Y Guo, C Tong, S Yang… - Oxidative Medicine …, 2020 - Wiley Online Library
The purpose of this study was to investigate the protective effect and mechanism of yeast
selenium (Se‐Y) on ochratoxin‐(OTA‐) induced nephrotoxicity of chickens. A total of 80 one …

Microcystin-leucine arginine exposure contributes to apoptosis and follicular atresia in mice ovaries by endoplasmic reticulum stress-upregulated Ddit3

H Liu, Z Tian, Y Guo, X Liu, Y Ma, X Du, R Wang… - Science of The Total …, 2021 - Elsevier
Microcystin-leucine arginine (MC-LR), an intracellular toxin to cause reproduction toxicity, is
produced by blooming cyanobacteria and widely distributed in eutrophic waters. It is …

Melatonin-mediated suppression of mtROS-JNK-FOXO1 pathway alleviates hypoxia-induced apoptosis in porcine granulosa cells

X Zhang, D Zhang, H Li, Z Liu, Y Yang, J Li, L Tang… - Antioxidants, 2023 - mdpi.com
Numerous studies have established that the hypoxic conditions within ovarian follicles
induce apoptosis in granulosa cells (GCs), a pivotal hallmark of follicular atresia. Melatonin …