Advances in heterocycle synthesis through photochemical carbene transfer reactions

ZY Xie, J Xuan - Chemical Communications, 2024 - pubs.rsc.org
Heterocyclic skeletons are commonly found in various bioactive molecules and
pharmaceutical compounds, making them crucial in areas such as medicinal chemistry …

Visible Light-Induced Reactions of Diazo Compounds and Their Precursors

Z Zhang, V Gevorgyan - Chemical Reviews, 2024 - ACS Publications
In recent years, visible light-induced reactions of diazo compounds have attracted
increasing attention in organic synthesis, leading to improvement of existing reactions, as …

Visible photons as ideal reagents for the activation of coloured organic compounds

L Di Terlizzi, L Nicchio, S Protti… - Chemical Society Reviews, 2024 - pubs.rsc.org
In recent decades, the traceless nature of visible photons has been exploited for the
development of efficient synthetic strategies for the photoconversion of colourless …

C–F bond functionalizations via fluorinated carbenes

Y Li, J Luo, Y Jiang - Organic Chemistry Frontiers, 2023 - pubs.rsc.org
Fluorinated carbenes take an important position in the synthesis of fluorine-containing
molecules in organic synthesis. When carbon centered carbenes are installed with fluorides …

Photoinduced arylative formal 4-endo-dig cyclization of propargyl alcohols/amines to access strained heterocycles

PV Reddy, A Nagireddy, JB Nanubolu, MS Reddy - Green Chemistry, 2024 - pubs.rsc.org
The development of green and sustainable approaches for the synthesis of small molecules
is always in demand. Oxetanes and azetidines are strained heterocycles that possess …

Light-Driven Intramolecular Cyclopropanation of Alkene-Tethered N-Tosylhydrazones: Synthesis of Fused-Cyclopropane γ-Lactones

P Yamini, A Babbar, D Yadagiri - Organic Letters, 2024 - ACS Publications
Fused-cyclopropane ring-containing γ-lactone compounds are versatile building blocks in
many fields, including the synthesis of biologically active compounds. Here, we report the …

Expanding the Chemical Space of Electrophilic β-Glycosyl β-Lactams through Photoinduced Diastereoselective Functionalization

EA Tordato, RO Gonçalves, LL Baldassari… - Organic …, 2024 - ACS Publications
Herein, we present a photoinduced diastereoselective C-3 functionalization of electrophilic β-
glycosyl β-lactams. The developed protocol is simple, mild, and scalable and explores the …

Syntheses and medicinal chemistry of spiro heterocyclic steroids

LL Romero-Hernández… - Beilstein Journal of …, 2024 - beilstein-journals.org
There is compelling evidence that incorporating a heterocyclic moiety into a steroid can alter
its pharmacological and pharmacokinetic properties, driving intense interest in the synthesis …

Chemical Methods for Construction of Spirocyclic β-Lactams and their Biological Importance

P Yadav, S Berry, A Bhalla - Synthesis, 2024 - thieme-connect.com
Spirocyclic β-lactams are a family of natural and synthetic chemicals with different biological
activity, including antibacterial properties and interaction with critical physiological targets …

Access to 2-oxoazetidine-3-carboxylic acid derivatives via thermal microwave-assisted Wolff rearrangement of 3-diazotetramic acids in the presence of nucleophiles

I Lyutin, V Krivovicheva, G Kantin… - Beilstein Journal of …, 2024 - beilstein-journals.org
In this work, we report an efficient approach to 2-oxoazetidine-3-carboxylic acid derivatives
based on a thermally promoted Wolff rearrangement of diazotetramic acids in the presence …