The clinical use of deep brain stimulation (DBS) is among the most important advances in
the clinical neurosciences in the past two decades. As a surgical tool, DBS can directly …

Parkinson's disease (PD) is a slowly progressive multisystem disorder affecting
dopaminergic neurons of the substantia nigra pars compacta (SNpc), which is characterized …

The greatest unmet therapeutic need in Parkinson's disease is the development of treatment
that slows the relentless progression of the neurodegenerative process. The concept of …

The aim of this review is to summarize that most relevant technologies used to evaluate gait
features and the associated algorithms that have shown promise to aid diagnosis and …

Background Freezing of gait (FOG) is a common, disabling symptom of Parkinson's disease
(PD), but the mechanisms and treatments of FOG remain great challenges for clinicians and …

A robust body of evidence from randomized controlled trials has established the efficacy of
deep brain stimulation (DBS) in reducing off time and dyskinesias in levodopa‐treated …

Deep brain stimulation (DBS) has become the treatment of choice for advanced stages of
Parkinson's disease, medically intractable essential tremor, and complicated segmental and …

During the last 30 years, deep brain stimulation (DBS) has evolved into the clinical standard
of care as a highly effective treatment for advanced Parkinson's disease. Careful patient …

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) or globus pallidum internus
(GPi) improves motor functions in patients with Parkinson's disease (PD) but may cause a …

Parkinson's disease (PD) is a common, degenerative disorder of the central nervous system.
Individuals experience predominantly extrapyramidal symptoms including resting tremor …