Uremic toxic blood-brain barrier disruption mediated by AhR activation leads to cognitive impairment during experimental renal dysfunction

M Bobot, L Thomas, A Moyon… - Journal of the …, 2020 - journals.lww.com
Background Uremic toxicity may play a role in the elevated risk of developing cognitive
impairment found among patients with CKD. Some uremic toxins, like indoxyl sulfate, are …

Cognitive function in kidney transplantation

A Jurgensen, AA Qannus, A Gupta - Current transplantation reports, 2020 - Springer
Abstract Purpose of Review Cognitive impairment is common in kidney transplant recipients
and affects quality of life, graft survival, morbidity, and mortality. In this review article we …

Age disparities in access to first and repeat kidney transplantation

Y Chen, B Churilla, JYB Ahn, EE Quint, S Sandal… - …, 2024 - journals.lww.com
Background. Evidence suggests that older patients are less frequently placed on the waiting
list for kidney transplantation (KT) than their younger counterparts. The trends and …

Defining the ethical considerations surrounding kidney transplantation for frail and cognitively impaired patients: a Delphi study of geriatric transplant experts

P Shrestha, SE Van Pilsum Rasmussen, EA King… - BMC geriatrics, 2022 - Springer
Background Among adult kidney transplant (KT) candidates, 21% are frail and 55% have
cognitive impairment, increasing the risk of pre-and post-KT mortality. Centers often assess …

[HTML][HTML] Changes in cognitive function after kidney transplantation: a longitudinal cohort study

A Gupta, JD Mahnken, J Bernal, P Sharma… - American Journal of …, 2024 - Elsevier
Rationale & Objective Kidney disease negatively affects cognition. We assessed the effect of
kidney transplantation (KT) on different cognitive domains. Study Design Prospective cohort …

Cognitive impairment and anxiety are prevalent in kidney transplant recipients

A Golenia, P Olejnik, N Żołek, E Wojtaszek… - Kidney and Blood …, 2023 - karger.com
Introduction: Cognitive impairment (CI) is common in end-stage kidney disease (ESKD),
including kidney transplant recipients. Patients with cognitive problems may find it difficult to …

Normalization of cerebral blood flow, neurochemicals, and white matter integrity after kidney transplantation

RJ Lepping, RN Montgomery, P Sharma… - Journal of the …, 2021 - journals.lww.com
Background CKD is associated with abnormalities in cerebral blood flow, cerebral
neurochemical concentrations, and white matter integrity. Each of these is associated with …

Patient perspectives on the use of frailty, cognitive function, and age in kidney transplant evaluation

P Shrestha, SE Van Pilsum Rasmussen… - AJOB Empirical …, 2022 - Taylor & Francis
Background The allocation of scarce deceased donor kidneys is a complex process.
Transplant providers are increasingly relying on constructs such as frailty and cognitive …

Cognitive function, access to kidney transplantation, and waitlist mortality among kidney transplant candidates with or without diabetes

NM Chu, Z Shi, CE Haugen, SP Norman… - American Journal of …, 2020 - Elsevier
Rationale & Objective Intact cognition is generally a prerequisite for navigating through and
completing evaluation for kidney transplantation. Despite kidney transplantation being …

Pre‐transplant cognitive screening is a poor predictor of post‐transplant cognitive status

A Gupta, RN Montgomery, K Young… - Clinical …, 2022 - Wiley Online Library
Introduction Transplant centers hesitate to transplant patients with cognitive impairment. It is
unclear if pre‐kidney transplant (KT) cognitive screening can predict post‐KT cognitive …