New types of antidiabetic agents are continually needed with diabetes becoming the
epidemic in the world. Indole alkaloids play an important role in natural products owing to …

The presented review is an attempt to summarize a huge volume of data on 5-ene-4-
thiazolidinones being a widely studied class of small molecules used in modern organic and …

Background Thiazolidinediones (TZDs), also called glitazones, are five-membered carbon
ring molecules commonly used for the management of insulin resistance and type 2 …

Thiazolidinedione (TZD) is one of the privileged heterocyclic rings and has shown many
biological applications in medicinal chemistry and drug discovery. This review covers the …

Thiazolidinediones are five-membered, heterocyclic compounds that possess a number of
pharmacological activities such as antihyperglycemic, antitumor, antiarthritic, anti …

Pancreatic Lipase (PL) is a key enzyme responsible for the digestion of 50%–70% of dietary
triglycerides, hence its inhibition is considered as a viable approach for the management of …

A series of indolylidinepyrazolones were synthesized using a simple, green, and effective
route and evaluated as anti-bacterial agents. The compounds were further studied via …

Colony-stimulating factor 1 receptor is a type III receptor protein tyrosine kinase belonging to
PDGFR family. CSF1R signaling is essential for differentiation, proliferation and survival of …

The present study reports a facile and green approach for the synthesis of thiazolidine/
oxazolidine derivatives 4 (a–u) in excellent yields (92–98%) with high purity. The protocol …

Knoevenagel condensation of isatin 1 with some nitriles 2 and with cyclohexane-1, 3-diones
4 using piperidinium acetate as catalyst in water at 100° C results in the formation of α, β …