Synthetic polypeptides: from polymer design to supramolecular assembly and biomedical application

Z Song, Z Han, S Lv, C Chen, L Chen, L Yin… - Chemical Society …, 2017 - pubs.rsc.org
Synthetic polypeptides from the ring-opening polymerization of N-carboxyanhydrides
(NCAs) are one of the most important biomaterials. The unique features of these synthetic …

Biodegradable stimuli-responsive polypeptide materials prepared by ring opening polymerization

Y Shen, X Fu, W Fu, Z Li - Chemical Society Reviews, 2015 - pubs.rsc.org
The stimuli-responsive polypeptides have drawn extensive attention because of their
promising applications in biotechnology considering their biocompatibility, biodegradability …

In situ gelling pH-and temperature-sensitive biodegradable block copolymer hydrogels for drug delivery

NK Singh, DS Lee - Journal of Controlled Release, 2014 - Elsevier
Stimuli-sensitive injectable polymeric hydrogels have been extensively investigated during
the past decade as bioactive agent delivery vehicles and for tissue engineering applications …

Stimuli‐responsive supramolecular hydrogels and their applications in regenerative medicine

J Hoque, N Sangaj, S Varghese - Macromolecular bioscience, 2019 - Wiley Online Library
Supramolecular hydrogels are a class of self‐assembled network structures formed via non‐
covalent interactions of the hydrogelators. These hydrogels capable of responding to …

Secondary structures of synthetic polypeptide polymers

C Bonduelle - Polymer Chemistry, 2018 - pubs.rsc.org
Synthetic peptide-based polymers represent a unique class of macromolecules able to
mimic the properties of natural proteins in materials sciences since (1) they present the …

Stimuli responsive synthetic polypeptides derived from N-carboxyanhydride (NCA) polymerisation

J Huang, A Heise - Chemical Society Reviews, 2013 - pubs.rsc.org
The progress in NCA polymerisation combined with advanced orthogonal functionalization
techniques as well as the integration with other controlled polymerisation techniques …

Thermoresponsive polymers: from natural proteins to amino acid based polymer synthesis

M Badreldin, PS Ambrosio, E Garanger… - Progress in Polymer …, 2023 - Elsevier
In polymer science, thermoresponsiveness refers to macromolecular systems that display a
marked and discontinuous change in their physical properties with temperature. Such smart …

Spider-silk inspired polymeric networks by harnessing the mechanical potential of β-sheets through network guided assembly

NJA Chan, D Gu, S Tan, Q Fu, TG Pattison… - Nature …, 2020 - nature.com
The high toughness of natural spider-silk is attributed to their unique β-sheet secondary
structures. However, the preparation of mechanically strong β-sheet rich materials remains a …

Self-assembly of peptide amphiphiles for drug delivery: the role of peptide primary and secondary structures

Z Song, X Chen, X You, K Huang, A Dhinakar… - Biomaterials …, 2017 - pubs.rsc.org
Peptide amphiphiles (PAs), functionalized with alkyl chains, are capable of self-assembling
into various nanostructures. Recently, PAs have been considered as ideal drug carriers due …

Tunable assembly of amphiphilic rod–coil block copolymers in solution

J Zhang, XF Chen, HB Wei, XH Wan - Chemical Society Reviews, 2013 - pubs.rsc.org
This review covers the recent progress in the research field of rod–coil block copolymers
(BCPs) containing rigid rod-like blocks and flexible coil-like blocks. Their assembly …