The emerging mechanisms and functions of microautophagy

L Wang, DJ Klionsky, HM Shen - Nature reviews Molecular cell biology, 2023 - nature.com
Abstract 'Autophagy'refers to an evolutionarily conserved process through which cellular
contents, such as damaged organelles and protein aggregates, are delivered to lysosomes …

[HTML][HTML] Selective autophagy of intracellular organelles: recent research advances

W Li, P He, Y Huang, YF Li, J Lu, M Li, H Kurihara… - Theranostics, 2021 - ncbi.nlm.nih.gov
Macroautophagy (hereafter called autophagy) is a highly conserved physiological process
that degrades over-abundant or damaged organelles, large protein aggregates and …

Lysosome biology in autophagy

WWY Yim, N Mizushima - Cell discovery, 2020 - nature.com
Autophagy is a major intracellular degradation system that derives its degradative abilities
from the lysosome. The most well-studied form of autophagy is macroautophagy, which …

Microautophagy–distinct molecular mechanisms handle cargoes of many sizes

S Schuck - Journal of Cell Science, 2020 - journals.biologists.com
Autophagy is fundamental for cell and organismal health. Two types of autophagy are
conserved in eukaryotes: macroautophagy and microautophagy. During macroautophagy …

The functional universe of membrane contact sites

WA Prinz, A Toulmay, T Balla - Nature reviews Molecular cell biology, 2020 - nature.com
Organelles compartmentalize eukaryotic cells, enhancing their ability to respond to
environmental and developmental changes. One way in which organelles communicate and …

Autophagy and the hallmarks of aging

S Kaushik, I Tasset, E Arias, O Pampliega… - Ageing research …, 2021 - Elsevier
Autophagy, an essential cellular process that mediates degradation of proteins and
organelles in lysosomes, has been tightly linked to cellular quality control for its role as part …

The coming of age of chaperone-mediated autophagy

S Kaushik, AM Cuervo - Nature reviews Molecular cell biology, 2018 - nature.com
Chaperone-mediated autophagy (CMA) was the first studied process that indicated that
degradation of intracellular components by the lysosome can be selective—a concept that is …

Autophagy and autophagy-related diseases: a review

T Ichimiya, T Yamakawa, T Hirano… - International journal of …, 2020 - mdpi.com
Autophagy refers to the process involving the decomposition of intracellular components via
lysosomes. Autophagy plays an important role in maintaining and regulating cell …

The ménage à trois of autophagy, lipid droplets and liver disease

Y Filali-Mouncef, C Hunter, F Roccio, S Zagkou… - Autophagy, 2022 - Taylor & Francis
Autophagic pathways cross with lipid homeostasis and thus provide energy and essential
building blocks that are indispensable for liver functions. Energy deficiencies are …

[HTML][HTML] Lysosomal microautophagy: an emerging dimension in mammalian autophagy

Y Kuchitsu, T Taguchi - Trends in Cell Biology, 2024 - cell.com
Autophagy is a self-catabolic process through which cellular components are delivered to
lysosomes for degradation. There are three types of autophagy, ie, macroautophagy …