A proper dialogue between spermatozoa and the egg is essential for conception of a new
individual in sexually reproducing animals. Ca2+ is crucial in orchestrating this unique event …

Sexually reproducing animals require an orchestrated communication between
spermatozoa and the egg to generate a new individual. Capacitation, a maturational …

Ion channels are extraordinarily efficient machines that move ions in diversely controlled
manners, allowing cells to rapidly exchange information with the outside world and with …

Generating new life in animals by sexual reproduction depends on adequate
communication between mature and competent male and female gametes. Ion channels are …

An important step in fertilization is the recognition and primary binding of the sperm cell to
the zona pellucida (ZP). Primary ZP binding proteins are located at the apical plasma …

Mammalian sperm require time in the female tract in order to be able to fertilize an egg. The
physiological changes that render the sperm able to fertilize are known as capacitation …

During the last seventy years, studies on mammalian sperm cells have demonstrated the
essential role of capacitation, hyperactivation and the acrosome reaction in the acquisition of …

Gamete cells are electrogenic, ie capable of responding to electrical stimuli and modifying
their electrical properties during the crucial periods of maturation and fertilization. Ion …

Mammalian sperm are unable to fertilize the egg immediately after ejaculation. In order to
gain fertilization competence, they need to undergo a series of biochemical and …

Fertilisation requires mature and competent male and female gametes. Sperm and egg must
find each other and fuse to generate a new individual. The codes that govern how sperm …