Despite the growing knowledge surrounding host–microbiome interactions, we are just
beginning to understand how the gut microbiome influences—and is influenced by—host …

Worldwide cancer incidence and mortality have always been a concern to the community.
The cancer mortality rate has generally declined over the years; however, there is still an …

Defects in the functions of RNA binding proteins (RBPs) are at the origin of many diseases;
however, targeting RBPs with conventional drugs has proven difficult. PROTACs are a new …

Ferropotsis is among the most important mechanisms of cancer suppression, which could be
harnessed for cancer therapy. However, no natural small-molecule compounds with cancer …

Alternative splicing is a key mechanism determinant for gene expression in metazoan.
During alternative splicing, non-coding sequences are removed to generate different mature …

Alternative pre-mRNA splicing is a tightly controlled process conducted by the spliceosome,
with the assistance of several regulators, resulting in the expression of different transcript …

The ability for cells to harness alternative splicing enables them to diversify their proteome in
order to carry out complex biological functions and adapt to external and internal stimuli. The …

Despite the advances in tumor identification and treatment, cancer remains the primary
driver of death around the world. Also, regular treatments for the disease are incapable of …

Although endometrial cancer is the most common cancer of the female reproductive tract, we
have little understanding of what controls endometrial cancer beyond the transcriptional …

Objective circular RNAs (circRNAs) have been reported to be essential regulators of multiple
malignant cancers. However, the functions of circRNAs in ovarian cancer need to be further …