Tissue adhesion is one of the most common postoperative complications, which is frequently
accompanied by inflammation, pain, and even dyskinesia, significantly reducing the quality …

The aqueous solubility of active drug moiety plays a crucial role in the development of an
efficacious formulation. The poor aqueous solubility of BCS class II and IV drugs is …

Purpose Rheumatoid arthritis is an autoimmune disorder that directly affects joints. However,
other body organs including heart, eyes, skin, blood vessels and lungs may also be affected …

Fenofibrate (FE) has been shown to markedly reduce the progression of diabetic retinopathy
and age-related macular degeneration in clinical trials and animal models. Owing to the …

The objective of this study was to improve the dissolution and solubility of dexibuprofen
(DEX) using hydroxypropyl beta cyclodextrin (HPβCD) inclusion complexes and also to …

Pericardial barrier destruction, inflammatory cell infiltration, and fibrous tissue hyperplasia,
trigger adhesions after cardiac surgery. There are few anti-adhesion materials that are both …

Palbociclib (PAL) is an anti-cancer molecule that is highly selective for CDK4/6 inhibition
and approved for the management of advanced breast cancer. Due to its down-and-out …

BCS class II drugs exhibit low aqueous solubility and high permeability. Such drugs often
have an incomplete or erratic absorption profile. This study aimed to predict the effects of β …

Diflunisal is a well-known drug for the treatment of rheumatoid arthritis, osteoarthritis,
primary dysmenorrhea, and colon cancer. This molecule belongs to the group of …

Bedaquiline fumarate (BQF), a BCS class-II drug, shows dissolution rate-dependent
absorption pattern, which results in poor biopharmaceutical performance. In this research …