Unraveling B cell trajectories at single cell resolution

D Morgan, V Tergaonkar - Trends in immunology, 2022 - cell.com
During adaptive immunity, B cells differentiate either into memory B cells or plasma cells and
produce antibodies against foreign antigens to fight infection. Additionally, they behave as …

A comprehensive review on the emerging role of long non-coding RNAs in the regulation of NF-κB signaling in inflammatory lung diseases

AA Bhat, O Afzal, N Agrawal, R Thapa… - International journal of …, 2023 - Elsevier
Public health globally faces significant risks from conditions like acute respiratory distress
syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and various …

NF‐κB as a regulator of cancer metastasis and therapy response: A focus on epithelial–mesenchymal transition

S Mirzaei, S Saghari, F Bassiri, R Raesi… - Journal of cellular …, 2022 - Wiley Online Library
Metastasis of tumor cells is a complex challenge and significantly diminishes the overall
survival and prognosis of cancer patients. The epithelial‐to‐mesenchymal transition (EMT) …

Signaling pathways and targeted therapies for psoriasis

J Guo, H Zhang, W Lin, L Lu, J Su… - Signal Transduction and …, 2023 - nature.com
Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

Macrophage polarization in inflammatory bowel disease

K Zhang, J Guo, W Yan, L Xu - Cell Communication and Signaling, 2023 - Springer
The growing prevalence of inflammatory bowel disease (IBD) has encouraged research
efforts, which have contributed to gradual improvements in our understanding of IBD …

Curcumin in the treatment of urological cancers: Therapeutic targets, challenges and prospects

M Hashemi, S Mirzaei, M Barati, ES Hejazi… - Life sciences, 2022 - Elsevier
Urological cancers include bladder, prostate and renal cancers that can cause death in
males and females. Patients with urological cancers are mainly diagnosed at an advanced …

Non-coding RNA-based regulation of inflammation

M Ashrafizadeh, A Zarrabi, E Mostafavi, AR Aref… - Seminars in …, 2022 - Elsevier
Inflammation is a multifactorial process and various biological mechanisms and pathways
participate in its development. The presence of inflammation is involved in pathogenesis of …

Serrated colorectal cancer: Preclinical models and molecular pathways

A Aiderus, N Barker, V Tergaonkar - Trends in Cancer, 2024 - cell.com
Serrated lesions are histologically heterogeneous, and detection can be challenging as
these lesions have subtle features that may be missed by endoscopy. Furthermore, while …

LNCing RNA to immunity

DC Peltier, A Roberts, P Reddy - Trends in immunology, 2022 - cell.com
Despite an ever-increasing appreciation of how protein-coding genes shape immune
responses, the molecular underpinnings of immune regulation remain incompletely …

The role of lncRNAs in regulating the intestinal mucosal mechanical barrier

S Chen, C Zhang, B He, R He, L Xu… - BioMed Research …, 2021 - Wiley Online Library
lncRNA is a transcript that is more than 200 bp in length. Currently, evidence has shown that
lncRNA is of great significance in cell activity, involved in epigenetics, gene transcription …