The older adult brain is less modular, more integrated, and less efficient at rest: A systematic review of large‐scale resting‐state functional brain networks in aging

HA Deery, R Di Paolo, C Moran, GF Egan… - …, 2023 - Wiley Online Library
The literature on large‐scale resting‐state functional brain networks across the adult
lifespan was systematically reviewed. Studies published between 1986 and July 2021 were …

Brain functional alterations in Type 2 Diabetes–A systematic review of fMRI studies

H Macpherson, M Formica, E Harris, RM Daly - Frontiers in …, 2017 - Elsevier
Abstract Type 2 Diabetes (T2DM) is emerging as a major global health issue. T2DM can
adversely affect cognition and increase dementia risk. This systematic review aimed to …

[HTML][HTML] A multimodal meta-analysis of regional structural and functional brain alterations in type 2 diabetes

L Yao, C Yang, W Zhang, S Li, Q Li, L Chen… - Frontiers in …, 2021 - Elsevier
Neuroimaging studies have identified brain structural and functional alterations of type 2
diabetes mellitus (T2DM) patients; however, there is no systematic information on the …

Linking atypical depression and insulin resistance-related disorders via low-grade chronic inflammation: Integrating the phenotypic, molecular and neuroanatomical …

ZD Sen, LV Danyeli, M Woelfer, F Lamers… - Brain, behavior, and …, 2021 - Elsevier
Insulin resistance (IR) and related disorders, such as T2DM, increase the risk of major
depressive disorder (MDD) and vice versa. Current evidence indicates that psychological …

Glucose fluctuations are linked to disrupted brain functional architecture and cognitive impairment

W Xia, Y Luo, YC Chen, H Chen… - Journal of Alzheimer's …, 2020 - content.iospress.com
Background: Type 2 diabetes mellitus (T2DM) accelerates cognitive decline, which is
believed to be triggered by aberrant neural activity. Objective: To explore how glucose …

Neurovascular decoupling in type 2 diabetes mellitus without mild cognitive impairment: Potential biomarker for early cognitive impairment

Y Yu, LF Yan, Q Sun, B Hu, J Zhang, Y Yang, YJ Dai… - Neuroimage, 2019 - Elsevier
Type 2 diabetes mellitus (T2DM) is a significant risk factor for mild cognitive impairment
(MCI) and the acceleration of MCI to dementia. The high glucose level induce disturbance of …

Cerebral blood flow alterations in type 2 diabetes mellitus: A systematic review and meta-analysis of arterial spin labeling studies

J Liu, X Yang, Y Li, H Xu, J Ren, P Zhou - Frontiers in Aging …, 2022 - frontiersin.org
Objective Arterial spin labeling (ASL) studies have revealed inconsistent regional cerebral
blood flow (CBF) alterations in patients with type 2 diabetes mellitus (T2DM). The aim of this …

Altered gray matter volume, functional connectivity, and degree centrality in early-onset type 2 diabetes mellitus

Y Feng, Y Li, X Tan, Y Liang, X Ma, Y Chen… - Frontiers in …, 2021 - frontiersin.org
Background: Structural and functional brain alterations that underlie cognitive decline have
been observed in elderly adults with type 2 diabetes mellitus (T2DM); however, whether …

Altered odor-induced brain activity as an early manifestation of cognitive decline in patients with type 2 diabetes

Z Zhang, B Zhang, X Wang, X Zhang, QX Yang… - Diabetes, 2018 - Am Diabetes Assoc
Type 2 diabetes is reported to be associated with olfactory dysfunction and cognitive
decline. However, whether and how olfactory neural circuit abnormalities involve cognitive …

Altered functional hubs and connectivity in type 2 diabetes mellitus without mild cognitive impairment

Y Li, Y Liang, X Tan, Y Chen, J Yang, H Zeng… - Frontiers in …, 2020 - frontiersin.org
Background: Type 2 diabetes mellitus (T2DM)-related cognitive decline is associated with
neuroimaging changes. However, only a few studies have focused on early functional …