Beyond the tail: the consequence of context in histone post-translational modification and chromatin research
EN Weinzapfel, KN Fedder-Semmes… - Biochemical …, 2024 - portlandpress.com
The role of histone post-translational modifications (PTMs) in chromatin structure and
genome function has been the subject of intense debate for more than 60 years. Though …
genome function has been the subject of intense debate for more than 60 years. Though …
[HTML][HTML] Safeguarding the epigenome through the cell cycle: a multitasking game
Highlights•Inheritance of parental histones maintain the epigenome.•Separate pathways
transfer H2A-H2B and H3-H4 to DNA daughter strands.•Mixing old and new histones …
transfer H2A-H2B and H3-H4 to DNA daughter strands.•Mixing old and new histones …
The N-terminal region of DNMT3A engages the nucleosome surface to aid chromatin recruitment
H Wapenaar, G Clifford, W Rolls, M Pasquier… - EMBO …, 2024 - embopress.org
Abstract DNA methyltransferase 3A (DNMT3A) plays a critical role in establishing and
maintaining DNA methylation patterns in vertebrates. Here we structurally and biochemically …
maintaining DNA methylation patterns in vertebrates. Here we structurally and biochemically …
Histone H2B ubiquitylation: Connections to transcription and effects on chromatin structure
Nucleosomes are major determinants of eukaryotic genome organization and regulation.
Many studies, incorporating a diversity of experimental approaches, have been focused on …
Many studies, incorporating a diversity of experimental approaches, have been focused on …
Connecting transcriptional dynamics with stress response: insights into the yeast factors Mog1 and Aim4
J Serrano-Quílez - 2024 - digital.csic.es
Post-translational histone modifications are essential for chromatin dynamics. Ubiquitination
of H2B at lysine 123 and H3 trimethylation at K4 are particularly important for cellular …
of H2B at lysine 123 and H3 trimethylation at K4 are particularly important for cellular …