Are the health attributes of lycopene related to its antioxidant function?

JW Erdman Jr, NA Ford, BL Lindshield - Archives of biochemistry and …, 2009 - Elsevier
A variety of epidemiological trials have suggested that higher intake of lycopene-containing
foods (primarily tomato products) or blood lycopene concentrations are associated with …

Protective effect of lycopene against chemical and natural toxins: A review

N Hedayati, MB Naeini, A Nezami… - …, 2019 - Wiley Online Library
People are exposed to a number of environmental, occupational, and therapeutic toxic
agents which may be natural or man made. These hazardous substances may manifest as …

Nrf2/HO-1 signaling pathway may be the prime target for chemoprevention of cisplatin-induced nephrotoxicity by lycopene

K Sahin, M Tuzcu, N Sahin, S Ali, O Kucuk - Food and Chemical Toxicology, 2010 - Elsevier
Cisplatin is used against various types of solid tumors. However, its use is limited by its
nephrotoxicity, with about 25–35% patients experiencing a significant decline in renal …

Royal jelly (honey bee) is a potential antioxidant against cadmium-induced genotoxicity and oxidative stress in albino mice

K Çavuşoğlu, K Yapar, E Yalçin - Journal of medicinal food, 2009 - liebertpub.com
Cadmium (Cd) is a highly toxic heavy metal that induces genotoxic damage in the body.
Besides, Cd induces oxidative damage in various tissues by altering antioxidant defence …

A tomato lycopene complex protects the kidney from cisplatin-induced injury via affecting oxidative stress as well as Bax, Bcl-2, and HSPs expression

A Dogukan, M Tuzcu, CA Agca, H Gencoglu… - Nutrition and …, 2011 - Taylor & Francis
Cisplatin-induced nephrotoxicity is related to an increase in oxidative stress in the kidney.
Lycopene, a carotenoid found in tomatoes, is a potent dietary antioxidant. In the present …

[HTML][HTML] Hydroalcoholic Myrciaria dubia (camu-camu) seed extracts prevent chromosome damage and act as antioxidant and cytotoxic agents

MAV Do Carmo, M Fidelis, CG Pressete… - Food Research …, 2019 - Elsevier
The camu-camu seeds, which comprehend about 20% of the fruit weight, is discarded
without taking benefit of their chemical components and potential application by the industry …

Modulation of inflammation by phytochemicals to enhance efficacy and reduce toxicity of cancer chemotherapy

TK Sahin, B Bilir, O Kucuk - Critical Reviews in Food Science and …, 2023 - Taylor & Francis
Abstract Treatment of cancer with chemotherapeutic drugs is associated with numerous
adverse effects as well as the eventual development of resistance to chemotherapy. There is …

Lycopene and chemotherapy toxicity

K Sahin, N Sahin, O Kucuk - Nutrition and cancer, 2010 - Taylor & Francis
Antineoplastic agents induce the production of free radicals and other reactive oxygen
species (ROS) in biological systems. Cytotoxic effects of antineoplastic drugs depend on …

Bixin and lycopene modulation of free radical generation induced by cisplatin–DNA interaction

AO Rios, LMG Antunes, M de LP Bianchi - Food Chemistry, 2009 - Elsevier
This work evaluated the modulation of reactive oxygen species (ROS) produced by the
cisplatin–human DNA interaction in a cell-free experimental model by the carotenoids bixin …

Protective Role of Ginkgo biloba Against Hepatotoxicity and Nephrotoxicity in Uranium-Treated Mice

K Yapar, K Çavuşoğlu, E Oruc, E Yalcin - Journal of medicinal food, 2010 - liebertpub.com
The aim of the present study was to investigate the protective role of Ginkgo biloba leaf
extract against uranium (U)-induced toxicity in Swiss albino mice. The mice were randomly …