Numerous polymeric biomaterials are implanted each year in human bodies. Among them,
drug delivery devices are potent novel powerful therapeutics for diseases which lack …

Corneal stromal ulceration is a devastating disorder that can cause blindness. Stromal
ulceration was once thought to be a physical dissolution process, which even now is …

Previous work established retinal expression of channelrhodopsin-2 (ChR2), an algal cation
channel gated by light, restored physiological and behavioral visual responses in otherwise …

Stem cell-based therapy for retinal degeneration is transitioning from the research stage to
the clinical stage and is being developed as a treatment across the globe. In clinical studies …

Purpose To determine the long-term outcome of human retinal pigment epithelium (RPE)
transplants in patients with advanced age-related macular degeneration (AMD). Methods …

The ultimate goal of transplantation is drug-free allograft acceptance, which is rarely
encountered in transplant recipients. Using a novel human-to-mouse “trans vivo” delayed …

Onchocerca volvulus infection has been associated with impaired cellular responses to
parasite antigens, an impairment that may also extend to nonparasite antigens. To …

Background. Allograft rejection is mediated by cytokines. As polymorphism in cytokine
genes can result in interindividual differences in cytokine production, we hypothesize that …

Objective To evaluate whether hemangiogenesis, lymphangiogenesis, and concomitant
invasion of mononuclear phagocytes occurring after high-risk corneal transplantation in …

Hair is a defining mammalian feature that serves as a hallmark of human communication.
Given the critical significance of hair in social, religious, and political contexts, it is important …