[HTML][HTML] Necroptosis, pyroptosis and apoptosis: an intricate game of cell death

D Bertheloot, E Latz, BS Franklin - Cellular & molecular immunology, 2021 - nature.com
Cell death is a fundamental physiological process in all living organisms. Its roles extend
from embryonic development, organ maintenance, and aging to the coordination of immune …

Apoptosis, pyroptosis, and necroptosis—Oh my! The many ways a cell can die

N Ketelut-Carneiro, KA Fitzgerald - Journal of molecular biology, 2022 - Elsevier
Cell death is an essential process in all living organisms and occurs through different
mechanisms. The three main types of programmed cell death are apoptosis, pyroptosis, and …

Targeting apoptosis in cancer therapy

BA Carneiro, WS El-Deiry - Nature reviews Clinical oncology, 2020 - nature.com
For over three decades, a mainstay and goal of clinical oncology has been the development
of therapies promoting the effective elimination of cancer cells by apoptosis. This …

Cell death, therapeutics, and the immune response in cancer

K Hänggi, B Ruffell - Trends in cancer, 2023 - cell.com
Induction of cell death is inexorably linked with cancer therapy, but this can also initiate
wound-healing processes that have been linked to cancer progression and therapeutic …

[HTML][HTML] Molecular mechanisms of radiation-induced cancer cell death: a primer

J Sia, R Szmyd, E Hau, HE Gee - Frontiers in cell and developmental …, 2020 - frontiersin.org
Radiation therapy (RT) is responsible for at least 40% of cancer cures, however treatment
resistance remains a clinical problem. There have been recent advances in understanding …

[HTML][HTML] Harnessing TRAIL-induced cell death for cancer therapy: a long walk with thrilling discoveries

A Montinaro, H Walczak - Cell Death & Differentiation, 2023 - nature.com
Tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) can induce apoptosis
in a wide variety of cancer cells, both in vitro and in vivo, importantly without killing any …

[HTML][HTML] Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies

G Pistritto, D Trisciuoglio, C Ceci, A Garufi… - Aging (albany …, 2016 - ncbi.nlm.nih.gov
Apoptosis is a form of programmed cell death that results in the orderly and efficient removal
of damaged cells, such as those resulting from DNA damage or during development …

Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy

S Von Karstedt, A Montinaro, H Walczak - Nature Reviews Cancer, 2017 - nature.com
The discovery that the tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) can
induce apoptosis of cancer cells without causing toxicity in mice has led to the in-depth study …

Graphene oxide nanoarchitectures in cancer biology: Nano-modulators of autophagy and apoptosis

A Taheriazam, GGY Abad, S Hajimazdarany… - Journal of Controlled …, 2023 - Elsevier
Nanotechnology is a growing field, with many potential biomedical applications of
nanomedicine for the treatment of different diseases, particularly cancer, on the horizon …

[HTML][HTML] P53 mutations in colorectal cancer-molecular pathogenesis and pharmacological reactivation

XL Li, J Zhou, ZR Chen, WJ Chng - World journal of …, 2015 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most common malignancies with high prevalence and
low 5-year survival. CRC is a heterogeneous disease with a complex, genetic and …