Some remarks on protein attribute prediction and pseudo amino acid composition

KC Chou - Journal of theoretical biology, 2011 - Elsevier
With the accomplishment of human genome sequencing, the number of sequence-known
proteins has increased explosively. In contrast, the pace is much slower in determining their …

Pseudo amino acid composition and its applications in bioinformatics, proteomics and system biology

KC Chou - Current Proteomics, 2009 - ingentaconnect.com
With the avalanche of protein sequences generated in the post-genomic age, it is highly
desired to develop automated methods for efficiently identifying various attributes of …

Cell-PLoc: a package of Web servers for predicting subcellular localization of proteins in various organisms

KC Chou, HB Shen - Nature protocols, 2008 - nature.com
Abstract Information on subcellular localization of proteins is important to molecular cell
biology, proteomics, system biology and drug discovery. To provide the vast majority of …

A multi-label classifier for predicting the subcellular localization of gram-negative bacterial proteins with both single and multiple sites

X Xiao, ZC Wu, KC Chou - PloS one, 2011 - journals.plos.org
Prediction of protein subcellular localization is a challenging problem, particularly when the
system concerned contains both singleplex and multiplex proteins. In this paper, by …

[HTML][HTML] Cell-PLoc 2.0: an improved package of web-servers for predicting subcellular localization of proteins in various organisms

KC Chou, HB Shen - Natural Science, 2010 - scirp.org
Cell-PLoc 2.0 is a package of web-servers evolved from Cell-PLoc (Chou, KC & Shen, HB,
Nature Protocols, 2008, 2: 153-162) by a top-down approach to improve the power for …

A new method for predicting the subcellular localization of eukaryotic proteins with both single and multiple sites: Euk-mPLoc 2.0

KC Chou, HB Shen - PloS one, 2010 - journals.plos.org
Information of subcellular locations of proteins is important for in-depth studies of cell
biology. It is very useful for proteomics, system biology and drug development as well …

EzyPred: a top–down approach for predicting enzyme functional classes and subclasses

HB Shen, KC Chou - Biochemical and biophysical research …, 2007 - Elsevier
Given a protein sequence, how can we identify whether it is an enzyme or non-enzyme? If it
is, which main functional class it belongs to? What about its sub-functional class? It is …

The modified Mahalanobis discriminant for predicting outer membrane proteins by using Chou's pseudo amino acid composition

H Lin - Journal of theoretical biology, 2008 - Elsevier
The outer membrane proteins (OMPs) are β-barrel membrane proteins that performed lots of
biology functions. The discriminating OMPs from other non-OMPs is a very important task for …

MultiP-SChlo: multi-label protein subchloroplast localization prediction with Chou's pseudo amino acid composition and a novel multi-label classifier

X Wang, W Zhang, Q Zhang, GZ Li - Bioinformatics, 2015 - academic.oup.com
Motivation: Identifying protein subchloroplast localization in chloroplast organelle is very
helpful for understanding the function of chloroplast proteins. There have existed a few …

Nuc-PLoc: a new web-server for predicting protein subnuclear localization by fusing PseAA composition and PsePSSM

HB Shen, KC Chou - Protein Engineering, Design & Selection, 2007 - academic.oup.com
The life processes of an eukaryotic cell are guided by its nucleus. In addition to the genetic
material, the cellular nucleus contains many proteins located at its different compartments …