Experimental and thermodynamic investigation of gemifloxacin solubility in supercritical CO2 for the production of nanoparticles
The effective use of the supercritical technology in the production of new pharmaceutical
formulations with greater bioavailability requires the determination of the solubility of …
formulations with greater bioavailability requires the determination of the solubility of …
[HTML][HTML] Measurement of metoprolol solubility in supercritical carbon dioxide; experimental and modeling study
SM Alshahrani, AM Alsubaiyel, MH Abduljabbar… - Case Studies in Thermal …, 2023 - Elsevier
Metoprolol is a beta-blocker agent, widely used to treat hypertension, and some heart
diseases. However, due to low bioavailability and short half-life of this drug, the dose and …
diseases. However, due to low bioavailability and short half-life of this drug, the dose and …
Investigating the Influence of Cosolvents on the Solubility of Febuxostat in Supercritical CO2: Experimental Analysis and Artificial Intelligence Study
OS Alsawad, AQ Mohammad AlHamad… - Journal of Chemical & …, 2024 - ACS Publications
Assessing the solubility of pharmaceutical compounds in supercritical carbon dioxide
(scCO2) is a fundamental prerequisite for advancing the application of supercritical …
(scCO2) is a fundamental prerequisite for advancing the application of supercritical …
[HTML][HTML] Thermodynamic and experimental analysis of drug nanoparticles preparation using supercritical thermal processing: Solubility of Chlorothiazide in different …
AJ Obaidullah - Case Studies in Thermal Engineering, 2023 - Elsevier
Background/purpose Chlorothiazide is a well-known diuretic and an antihypertensive drug
with poor solubility and permeability and thus low bioavailability. Producing nanoparticles of …
with poor solubility and permeability and thus low bioavailability. Producing nanoparticles of …
Pregabalin solubility in supercritical green solvent: a comprehensive experimental and theoretical-intelligent assessment
To find an effective formulation of active pharmaceutical ingredients through supercritical
fluid (SCF) technology, it is essential to measure the solubility of API. The solubility of …
fluid (SCF) technology, it is essential to measure the solubility of API. The solubility of …
Nanomedicine formulation using green supercritical processing: experimental solubility measurement and theoretical investigation
To develop effective pharmaceutical formulations using supercritical carbon dioxide (scCO2)
techniques, it is necessary to obtain the solubility of the medicinal ingredients in scCO2. In …
techniques, it is necessary to obtain the solubility of the medicinal ingredients in scCO2. In …
[HTML][HTML] Binary and ternary approach of solubility of Rivaroxaban for preparation of developed nano drug using supercritical fluid
M Askarizadeh, N Esfandiari, B Honarvar… - Arabian Journal of …, 2024 - Elsevier
This study addressed the solubility of Rivaroxaban in supercritical carbon dioxide at a
temperature range of 308–338 K and a pressure range of 12–30 MPa with and without a Co …
temperature range of 308–338 K and a pressure range of 12–30 MPa with and without a Co …
Simulation and Optimization: A New Direction in Supercritical Technology Based Nanomedicine
In recent years, nanomedicines prepared using supercritical technology have garnered
widespread research attention due to their inherent attributes, including structural stability …
widespread research attention due to their inherent attributes, including structural stability …
Comprehensive study of medications solubility in supercritical CO2 with and without co-solvent; Laboratory, theoretical, and intelligent approaches
CY Hsu, DJ Jasim, P Bansal, N Juraev… - Journal of Molecular …, 2024 - Elsevier
Determining the dissolution characteristics of medicines in supercritical CO 2 is vital for
formulating innovative drug delivery systems through an efficient supercritical process. This …
formulating innovative drug delivery systems through an efficient supercritical process. This …
Advancing nanomedicine production via green thermal supercritical processing: Laboratory measurement and thermodynamic modeling
TN Alharby, MM Algahtani, J Alanazi… - Journal of Molecular …, 2023 - Elsevier
Chlorpromazine is an antipsychotic medicine which is used to treat psychotic disorders,
nausea and vomiting. Based on the Biopharmaceutical Classification System (BCS), this …
nausea and vomiting. Based on the Biopharmaceutical Classification System (BCS), this …