Emergence of antibiotic resistant pathogenic bacteria poses a serious public health
challenge worldwide. However, antibiotic resistance genes are not confined to the clinic; …

Multidrug resistance is a key determinant of cancer chemotherapy failure. One of the major
causes of multidrug resistance is the enhanced efflux of drugs by membrane ABC …

Multidrug resistance (MDR) is becoming a significant obstacle for chemotherapeutic
treatment in the battle against malignant cancers. Because of the emergence of MDR, higher …

Abstract Ethnopharmacological relevance Armillaria mellea (Vahl. ex. Fr.) Karst is an
important traditional Chinese medicine used in dispelling wind and removing obstruction in …

The pharmaceutical research sector's inability to develop new drugs has made it
challenging to combat microbial resistance. Secondary metabolites from plant extracts have …

Streptococcus suis is an important pathogen in both pigs and humans. Although the
diseases associated with S. suis can typically be treated with antibiotics, such use has …

Antibiotic-producing microorganisms usually require one or more self-resistance
determinants to survive antibiotic production. The effectors of these mechanisms are …

Natural or synthesized antioxidants are compounds that can inhibit or delay the onset
oxidation. Due to the wide availability of natural antioxidants and the increasing concerns on …

Bacterial multidrug transporter DrrAB exhibits overlapping substrate specificity with
mammalian P-glycoprotein. DrrA hydrolyzes ATP, and the energy is transduced to carrier …

Mammalian ATP-binding cassette (ABC) subfamily F member 3 (ABCF3) is a class 2 ABC
protein that has previously been identified as a partner of the mouse flavivirus resistance …