Promising artificial intelligence-machine learning-deep learning algorithms in ophthalmology

L Balyen, T Peto - The Asia-Pacific Journal of Ophthalmology, 2019 - journals.lww.com
The lifestyle of modern society has changed significantly with the emergence of artificial
intelligence (AI), machine learning (ML), and deep learning (DL) technologies in recent …

Nanomaterial-based ophthalmic drug delivery

G Xie, S Lin, F Wu, J Liu - Advanced drug delivery reviews, 2023 - Elsevier
The low bioavailability and side effects of conventional drugs for eye disease necessitate the
development of efficient drug delivery systems. Accompanying the developments of …

[HTML][HTML] Intravitreal hydrogels for sustained release of therapeutic proteins

BC Ilochonwu, A Urtti, WE Hennink… - Journal of Controlled …, 2020 - Elsevier
This review highlights how hydrogel formulations can improve intravitreal protein delivery to
the posterior segment of the eye in order to increase therapeutic outcome and patient …

Fibroin nanoparticles: A promising drug delivery system

DT Pham, W Tiyaboonchai - Drug delivery, 2020 - Taylor & Francis
Fibroin is a dominant silk protein that possesses ideal properties as a biomaterial for drug
delivery. Recently, the development of fibroin nanoparticles (FNPs) for various biomedical …

Lipid nanoparticles for the posterior eye segment

L Bonilla, M Espina, P Severino, A Cano, M Ettcheto… - Pharmaceutics, 2021 - mdpi.com
This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles,
Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for …

Recent advances in drug delivery systems for glaucoma treatment

KD Patel, LB Silva, Y Park, T Shakouri… - Materials Today …, 2022 - Elsevier
Glaucoma is a chronic eye disease and the second most leading cause of irreversible
impaired vision in the world, which is primarily linked with high intraocular pressure (IOP) …

Challenges and strategies for ocular posterior diseases therapy via non-invasive advanced drug delivery

Q Qi, Y Wei, X Zhang, J Guan, S Mao - Journal of Controlled Release, 2023 - Elsevier
Posterior segment diseases, such as age-related macular degeneration (AMD) and diabetic
retinopathy (DR) are vital factor that seriously threatens human vision health and quality of …

Ocular delivery of bimatoprost-loaded solid lipid nanoparticles for effective management of glaucoma

SD Satyanarayana, AS Abu Lila, A Moin, EH Moglad… - Pharmaceuticals, 2023 - mdpi.com
Glaucoma is a progressive optic neuropathy characterized by a rise in the intraocular
pressure (IOP) leading to optic nerve damage. Bimatoprost is a prostaglandin analogue …

Doped graphene quantum dots for intracellular multicolor imaging and cancer detection

E Campbell, MT Hasan… - ACS Biomaterials …, 2019 - ACS Publications
Despite significant advances of nanomedicine, the issues of biocompatibility, accumulation-
derived toxicity, and the lack of sensing and in vivo imaging capabilities hamper the …

Trends in formulation approaches for sustained drug delivery to the posterior segment of the eye

A Biswas, AD Choudhury, AC Bisen, S Agrawal… - AAPS …, 2023 - Springer
The eye, an intricate organ comprising physical and physiological barriers, poses a
significant challenge for ophthalmic physicians seeking to treat serious ocular diseases …