[图书][B] RNA, the epicenter of genetic information

J Mattick, P Amaral - 2023 - library.oapen.org
The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Molecular mechanisms underlying origin and diversification of the angiosperm flower

G Theissen, R Melzer - Annals of botany, 2007 - academic.oup.com
Background Understanding the mode and mechanisms of the evolution of the angiosperm
flower is a long-standing and central problem of evolutionary biology and botany. It has …

[HTML][HTML] Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences

MF Berger, G Badis, AR Gehrke, S Talukder… - Cell, 2008 - cell.com
Most homeodomains are unique within a genome, yet many are highly conserved across
vast evolutionary distances, implying strong selection on their precise DNA-binding …

CHARGE and Kabuki syndromes: gene-specific DNA methylation signatures identify epigenetic mechanisms linking these clinically overlapping conditions

DT Butcher, C Cytrynbaum, AL Turinsky, MT Siu… - The American Journal of …, 2017 - cell.com
Epigenetic dysregulation has emerged as a recurring mechanism in the etiology of
neurodevelopmental disorders. Two such disorders, CHARGE and Kabuki syndromes …

[HTML][HTML] RETRACTED: The Noncoding RNA Mistral Activates Hoxa6 and Hoxa7 Expression and Stem Cell Differentiation by Recruiting MLL1 to Chromatin

S Bertani, S Sauer, E Bolotin, F Sauer - 2011 - Elsevier
The epigenetic activator Mixed lineage leukemia 1 (MLL1) is paramount for embryonic
development and hematopoiesis. Here, we demonstrate that the long, noncoding RNA …

Transcriptional Regulation and Implications for Controlling Hox Gene Expression

Z Afzal, R Krumlauf - Journal of Developmental Biology, 2022 - mdpi.com
Hox genes play key roles in axial patterning and regulating the regional identity of cells and
tissues in a wide variety of animals from invertebrates to vertebrates. Nested domains of Hox …

Genes of the most conserved WOX clade in plants affect root and flower development in Arabidopsis

Y Deveaux, C Toffano-Nioche, G Claisse… - BMC Evolutionary …, 2008 - Springer
Abstract Background The Wuschel related homeobox (WOX) family proteins are key
regulators implicated in the determination of cell fate in plants by preventing cell …

Chromatoid body and small RNAs in male germ cells

O Meikar, M Da Ros, H Korhonen, N Kotaja - Reproduction, 2011 - rep.bioscientifica.com
The distribution of nuclear oestrogen receptor alpha (ER-alpha) in the sex organs of fetal
and newborn mice has been investigated immunohistochemically. There was no visible ER …

MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis

AG Hoss, VK Kartha, X Dong, JC Latourelle… - PLoS …, 2014 - journals.plos.org
Transcriptional dysregulation has long been recognized as central to the pathogenesis of
Huntington's disease (HD). MicroRNAs (miRNAs) represent a major system of post …

HOXA9 transcription factor is a double-edged sword: from development to cancer progression

US Shenoy, D Adiga, F Alhedyan… - Cancer and Metastasis …, 2024 - Springer
The HOXA9 transcription factor serves as a molecular orchestrator in cancer stemness,
epithelial-mesenchymal transition (EMT), metastasis, and generation of the tumor …