Model systems for regeneration: planarians
M Ivankovic, R Haneckova, A Thommen… - …, 2019 - journals.biologists.com
Planarians are a group of flatworms. Some planarian species have remarkable regenerative
abilities, which involve abundant pluripotent adult stem cells. This makes these worms a …
abilities, which involve abundant pluripotent adult stem cells. This makes these worms a …
Nervous system development and regeneration in freshwater planarians
KG Ross, KW Currie, BJ Pearson… - Wiley Interdisciplinary …, 2017 - Wiley Online Library
Planarians have a long history in the fields of developmental and regenerative biology.
These animals have also sparked interest in neuroscience due to their neuroanatomy …
These animals have also sparked interest in neuroscience due to their neuroanatomy …
A generic and cell-type-specific wound response precedes regeneration in planarians
Regeneration starts with injury. Yet how injuries affect gene expression in different cell types
and how distinct injuries differ in gene expression remain unclear. We defined the …
and how distinct injuries differ in gene expression remain unclear. We defined the …
PlanMine–a mineable resource of planarian biology and biodiversity
H Brandl, HK Moon, M Vila-Farré, SY Liu… - Nucleic acids …, 2016 - academic.oup.com
Planarian flatworms are in the midst of a renaissance as a model system for regeneration
and stem cells. Besides two well-studied model species, hundreds of species exist …
and stem cells. Besides two well-studied model species, hundreds of species exist …
Animal regeneration in the era of transcriptomics
Animal regeneration, the ability to restore a lost body part, is a process that has fascinated
scientists for centuries. In this review, we first present what regeneration is and how it relates …
scientists for centuries. In this review, we first present what regeneration is and how it relates …
Wounding response in Porifera (sponges) activates ancestral signaling cascades involved in animal healing, regeneration, and cancer
Upon injury, the homeostatic balance that ensures tissue function is disrupted. Wound-
induced signaling triggers the recovery of tissue integrity and offers a context to understand …
induced signaling triggers the recovery of tissue integrity and offers a context to understand …
Comparative transcriptomic analyses and single-cell RNA sequencing of the freshwater planarian Schmidtea mediterranea identify major cell types and pathway …
LS Swapna, AM Molinaro, N Lindsay-Mosher… - Genome biology, 2018 - Springer
Abstract Background In the Lophotrochozoa/Spiralia superphylum, few organisms have as
high a capacity for rapid testing of gene function and single-cell transcriptomics as the …
high a capacity for rapid testing of gene function and single-cell transcriptomics as the …
β-catenin-dependent control of positional information along the AP body axis in planarians involves a teashirt family member
Wnt/β-catenin signaling regulates tissue homeostasis and regeneration in metazoans. In
planarians—flatworms with high regenerative potential—Wnt ligands are thought to control …
planarians—flatworms with high regenerative potential—Wnt ligands are thought to control …
A meta-analysis of bioelectric data in cancer, embryogenesis, and regeneration
Developmental bioelectricity is the study of the endogenous role of bioelectrical signaling in
all cell types. Resting potentials and other aspects of ionic cell physiology are known to be …
all cell types. Resting potentials and other aspects of ionic cell physiology are known to be …
The first inorganic mitogens: Cerium oxide and cerium fluoride nanoparticles stimulate planarian regeneration via neoblastic activation
We report the first experimental evidence for the mitogenic action of cerium (IV) oxide and
cerium (III) fluoride nanoparticles (CONs and CFNs) on the regeneration of a whole …
cerium (III) fluoride nanoparticles (CONs and CFNs) on the regeneration of a whole …