Salivary gland function, development, and regeneration

AM Chibly, MH Aure, VN Patel… - Physiological …, 2022 - journals.physiology.org
Salivary glands produce and secrete saliva, which is essential for maintaining oral health
and overall health. Understanding both the unique structure and physiological function of …

Saliva: An all-rounder of our body

E Roblegg, A Coughran, D Sirjani - European Journal of Pharmaceutics …, 2019 - Elsevier
Saliva is a multifaceted bodily fluid that is often taken for granted but is indispensable for oral
health and overall well-being in humans. Although mainly comprised of water (99.5%) …

Osteonecrosis of the jaw and antiresorptive agents in benign and malignant diseases: a critical review organized by the ECTS

AD Anastasilakis, J Pepe, N Napoli… - The Journal of …, 2022 - academic.oup.com
Context Antiresorptive therapy significantly reduces fracture risk in patients with benign bone
disease and skeletal-related events (SREs) in patients with bone metastases (BM) …

Managing xerostomia and salivary gland hypofunction: executive summary of a report from the American Dental Association Council on Scientific Affairs

JM Plemons, I Al-Hashimi, CL Marek - The Journal of the American Dental …, 2014 - Elsevier
ABSTRACT Background and Overview Xerostomia, also known as “dry mouth,” is a common
but frequently overlooked condition that is typically associated with salivary gland …

Xerostomia induced by radiotherapy: an overview of the physiopathology, clinical evidence, and management of the oral damage

R Pinna, G Campus, E Cumbo, I Mura… - … and clinical risk …, 2015 - Taylor & Francis
Background The irradiation of head and neck cancer (HNC) often causes damage to the
salivary glands. The resulting salivary gland hypofunction and xerostomia seriously reduce …

Use of amifostine for cytoprotection during radiation therapy: a review

M King, S Joseph, A Albert, TV Thomas, MR Nittala… - Oncology, 2020 - karger.com
Background: Radiation therapy is a cornerstone of the therapeutic modalities used in
modern oncology. However, it is sometimes limited in its ability to achieve optimal tumor …

Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction

BJ Baum, I Alevizos, C Zheng… - Proceedings of the …, 2012 - National Acad Sciences
No conventional therapy exists for salivary hypofunction in surviving head and neck cancer
patients with Radiation Therapy Oncology Group late grade 2–3 toxicity. We conducted a …

Adverse effects of radioactive iodine-131 treatment for differentiated thyroid carcinoma

A Fard-Esfahani, A Emami-Ardekani… - Nuclear medicine …, 2014 - journals.lww.com
Use of radioactive iodine is an essential adjuvant treatment strategy after thyroidectomy in
patients with differentiated thyroid carcinoma. Although generally safe, radioiodine therapy …

Current ideas to reduce or salvage radiation damage to salivary glands

A Vissink, P Van Luijk, JA Langendijk… - Oral diseases, 2015 - Wiley Online Library
Radiation‐induced hyposalivation is still a major problem after radiotherapy for head and
neck cancer. Current and promising new thoughts to reduce or salvage radiation damage to …

Oral and dental late effects in survivors of childhood cancer: a Children's Oncology Group report

KE Effinger, CA Migliorati, MM Hudson… - Supportive Care in …, 2014 - Springer
Purpose Multi-modality therapy has resulted in improved survival for childhood
malignancies. The Children's Oncology Group Long-Term Follow-Up Guidelines for …