Coenzyme A (CoA) is an essential cofactor in all living organisms. It is involved in a large
number of biochemical processes functioning either as an activator of molecules with …

Coenzyme A (CoA) is a vital and ubiquitous cofactor required in a vast number of enzymatic
reactions and cellular processes. To date, four rare human inborn errors of CoA biosynthesis …

Inherited retinal dystrophies are characterized by photoreceptor death. Oxidative stress
usually occurs, increasing vision loss, and oxidative damage is often reported in retinitis …

Abstract Early B-cell factor-1 (EBF1) is a transcription factor with an important role in cell
lineage specification and commitment during the early stage of cell maturation. Originally …

The nuclear factor NF-kB is the master transcription factor in the inflammatory process by
modulating the expression of pro-inflammatory genes. However, an additional level of …

Coenzyme A (CoA) is an essential cofactor in all living organisms, being involved in a large
number of chemical reactions. Sequence variations in pantothenate kinase 2 (PANK2), the …

Zebrafish has proven to be a versatile and reliable experimental in vivo tool to study human
hematopoiesis and model hematological malignancies. Transgenic technologies enable the …

Purpose: This study aims to investigate the relationship among STRA6, circadian rhythm,
and choroidal neovascularization (CNV) formation, as well as the regulatory mechanism of …

Mutations in pank2 gene encoding pantothenate kinase 2 determine a pantothenate kinase-
associated neurodegeneration, a rare disorder characterized by iron deposition in the …

神经退行性变伴脑铁沉积症是一组由基因变异导致的罕见的神经遗传变性疾病,
总体发病率为2/1 000 000~ 3/1 000 000, 该病以铁离子沉积于中枢神经系统 …