Host Cell Targets of Released Lipid and Secreted Protein Effectors of Mycobacterium tuberculosis

J Augenstreich, V Briken - Frontiers in cellular and infection …, 2020 - frontiersin.org
Mycobacterium tuberculosis (Mtb) is a very successful pathogen, strictly adapted to humans
and the cause of tuberculosis. Its success is associated with its ability to inhibit host cell …

Exploring the role of the protein tyrosine kinase a (PtkA) in mycobacterial intracellular survival

S Jaiswal, S Kumar, EV de la Cruz - Tuberculosis, 2023 - Elsevier
Mycobacterium tuberculosis (Mtb) continues to define new paradigms of host-pathogen
interaction. There are several host proteins known which are regulated by Mtb infection. The …

Protein Tyrosine and Serine/Threonine phosphorylation in oral bacterial dysbiosis and bacteria-host interaction

L Ren, D Shen, C Liu, Y Ding - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
The human oral cavity harbors approximately 1,000 microbial species, and dysbiosis of the
microflora and imbalanced microbiota-host interactions drive many oral diseases, such as …

3-Heterosubstituted Benzofurans from Hydroxyphenyl Propargyl Alcohols via ortho-Quinone Methide through a Metal-/Catalyst-Free Conjugate Addition/Oxy …

M Rajesh, MKR Singam, RK Gadi, M Sridhar Reddy - ACS omega, 2018 - ACS Publications
A facile route to 3-sulfonylated and 3-(1-benzotriazolyl)-benzofurans is achieved from
readily available o-hydroxyphenyl propargyl alcohols (o-HPPAs) and bench-top sodium …

A brief report on the of mycobacterial proteins regulated by the loss of PtkA in Mtb-H37Ra

S Jaiswal, KK Srivasatava - BioRxiv, 2023 - biorxiv.org
Kinase-phosphatase signaling plays an important role in cellular signaling pathways. The
genome of Mycobacterium tuberculosis,(the causative agent of tuberculosis), is embossed …

Phosphoproteomics of Mycobacterium-host interaction and inspirations for novel measures against tuberculosis

Z Wang, J Xie - Cellular Signalling, 2022 - Elsevier
Tuberculosis caused by Mycobacterium tuberculosis (Mtb) remains a tremendous global
public health concern. Deciphering the biology of the pathogen and its interaction with host …

ATP synthase, an essential enzyme in growth and multiplication is modulated by protein tyrosine phosphatase in Mycobacterium tuberculosis H37Ra

A Chatterjee, S Pandey, E Dhamija, S Jaiswal… - Biochimie, 2019 - Elsevier
Mycobacterium tuberculosis (Mtb) protein tyrosine phosphatase (PtpA) has so far been
known to control intracellular survival of mycobacteria; whereas the ATP synthase which is …

Investigating the Cellular Role of LamA Phosphorylation on Asymmetric Polar Growth in Mycobacteria

CM Gwin - 2024 - search.proquest.com
From dividing labor within communities to having a flexible response to environmental
insults, phenotypic heterogeneity provides numerous benefits to microorganisms …

Insights on the Functional Importance of Molecular Motions in Phosphatases

EX Zavala - 2024 - search.proquest.com
Enzymes are biomolecules that catalyze biological reactions, and as such, demand
thorough investigation so that manipulation of their associated biological processes can be …