Apoptosis is a physiological cell suicide program that is critical for the development and
maintenance of healthy tissues. Dysregulation of cell death pathways occur in cancer …

Figure 1 Screenshot of a session with Clustal X in split-window mode for profile alignment.
Archaeal TFIIB sequences (lower window) are aligned with prealigned eukaryotic TFIIBs …

Clustal Omega is a package for making multiple sequence alignments of amino acid or
nucleotide sequences, quickly and accurately. It is a complete upgrade and rewrite of earlier …

Spatial structures of proteins are closely related to protein functions. Integrating protein
structures improves the performance of protein–protein interaction (PPI) prediction …

The Clustal W and Clustal X multiple sequence alignment programs have been completely
rewritten in C++. This will facilitate the further development of the alignment algorithms in the …

The sensitivity of the commonly used progressive multiple sequence alignment method has
been greatly improved for the alignment of divergent protein sequences. Firstly, individual …

ACE2, the first known human homologue of angiotensin-converting enzyme (ACE), was
identified from 5′ sequencing of a human heart failure ventricle cDNA library. ACE2 has an …

Probabilistic models are becoming increasingly important in analysing the huge amount of
data being produced by large-scale DNA-sequencing efforts such as the Human Genome …

The Clustal programs are widely used for carrying out automatic multiple alignment of
nucleotide or amino acid sequences. The most familiar version is ClustalW, which uses a …

Using in silico analysis we studied a novel family of repetitive DNA sequences that is
present among both domains of the prokaryotes (Archaea and Bacteria), but absent from …