A previous comparative-genomic study of large nuclear and cytoplasmic DNA viruses
(NCLDVs) of eukaryotes revealed the monophyletic origin of four viral families: poxviruses …

Poxviruses comprise a large family of viruses characterized by a large, linear dsDNA
genome, a cytoplasmic site of replication and a complex virion morphology. The most …

Vaccinia virus is a large enveloped poxvirus with more than 200 genes in its genome.
Although many poxvirus genomes have been sequenced, knowledge of the host and viral …

The protein content of vaccinia virus mature virions, purified by rate zonal and isopycnic
centrifugations and solubilized by SDS or a solution of urea and thiourea, was determined …

Studies of the functional proteins encoded by the poxvirus genome provide information
about the composition of the virus as well as individual virus-virus protein and virus-host …

Poxviruses are large enveloped viruses that replicate in the cytoplasm of vertebrate or
invertebrate cells. At least six virus-encoded proteins are required for synthesis and …

Poxviruses encode many if not all of the proteins required for viral genome replication in the
cytoplasm of the host cell. In this context, we investigated the function of the vaccinia virus …

The vaccinia virion is a membraned, slightly flattened, barrel-shaped particle, with a complex
internal structure featuring a biconcave core flanked by lateral bodies. Although the …

The vaccinia virus A11R gene has orthologs in all known poxvirus genomes, and the A11
protein has been previously reported to interact with the putative DNA packaging protein …

Ascoviruses (family Ascoviridae) are double-stranded DNA viruses with circular genomes
that attack lepidopterans, where they produce large, enveloped virions, 150 by 400 nm, and …