Glioma resection is associated with prolonged survival, but neuro-oncological trials have
frequently refrained from quantifying the extent of resection. The Response Assessment in …

Purpose of Review IDH-mutant low-grade gliomas (LGG) have emerged as a distinct clinical
and molecular entity with unique treatment considerations. Here, we review updates in IDH …

Purpose: While MGMT promoter methylation (m MGMT) is predictive of response to
alkylating chemotherapy and guides treatment decisions in glioblastoma, its role in grade 2 …

Background Disparities in treatment and outcomes disproportionately affect minority ethnic
and racial populations in many surgical fields. Although substantial research in racial …

Purpose: In a post hoc analysis of the CATNON trial (NCT00626990), we explored whether
adding temozolomide to radiotherapy improves outcome in patients with IDH1/2 wildtype …

Importance O 6-methylguanine-DNA methyltransferase (MGMT [OMIM156569]) promoter
methylation (mMGMT) is predictive of response to alkylating chemotherapy for glioblastomas …

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OBJECTIVE Genomic analysis in neurooncology has underscored the importance of
understanding the patterns of survival in different molecular subtypes within gliomas and …

Purpose Since the introduction of the molecular definition of oligodendrogliomas based on
isocitrate dehydrogenase (IDH)-status and the 1p19q-codeletion, it has become increasingly …

Background With refinements in diagnosis and therapy of gliomas, the importance of
survival time as the sole outcome parameter has decreased, and patient-centered outcome …