Altered synaptic structure and function is a major hallmark of fragile X syndrome (FXS),
autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are …

Autism spectrum disorder (ASD) encompasses a group of multifactorial neurodevelopmental
disorders characterized by impaired social communication, social interaction and repetitive …

Tightly regulated transport of messenger ribonucleoprotein (mRNP) granules to diverse
locations of dendrites and axons is essential for appropriately timed protein synthesis within …

Learning and memory rely on long-lasting, synapse-specific modifications. Although
postsynaptic forms of plasticity typically require local protein synthesis, whether and how …

The complex morphology of neurons, the specific requirements of synaptic
neurotransmission and the accompanying metabolic demands create a unique challenge for …

Individuals with autism spectrum disorder (ASD) exhibit a diverse range of behavioral
features and genetic backgrounds, but whether different genetic forms of autism involve …

Abstract Disrupted in schizophrenia 1 (DISC1) is an important hub protein, forming
multimeric complexes by self‐association and interacting with a large number of synaptic …

Regulation of the microtubule cytoskeleton is crucial for the development and maintenance
of neuronal architecture, and recent studies have highlighted the significance of regulated …

ABSTRACT RNA localization to neuronal dendrites and axons is increasingly recognized as
a significant and widespread mechanism of gene expression control in neurons. High …

Neurodevelopmental disorders have a strong genetic component, but despite widespread
efforts, the specific genetic factors underlying these disorders remain undefined for a large …