Preclinical and clinical effects of Nigella sativa and its constituent, thymoquinone: A review
Z Gholamnezhad, S Havakhah… - Journal of …, 2016 - Elsevier
Ethnopharmacological relevance Nigella sativa (N. sativa) L.(Ranunculaceae), well known
as black cumin, has been used as a herbal medicine that has a rich historical background. It …
as black cumin, has been used as a herbal medicine that has a rich historical background. It …
[HTML][HTML] Review on clinical trials of black seed (Nigella sativa) and its active constituent, thymoquinone
A Tavakkoli, V Mahdian, BM Razavi… - Journal of …, 2017 - ncbi.nlm.nih.gov
Objectives Nigella sativa (black seed or black cumin), which belongs to the Ranunculacea
family, is an annual herb with many pharmacological properties. Among its many active …
family, is an annual herb with many pharmacological properties. Among its many active …
Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells
The use of innocuous naturally occurring compounds to overcome drug resistance and
cancer recalcitrance is now in the forefront of cancer research. Thymoquinone (TQ) is a …
cancer recalcitrance is now in the forefront of cancer research. Thymoquinone (TQ) is a …
Therapeutic implications of black seed and its constituent thymoquinone in the prevention of cancer through inactivation and activation of molecular pathways
The cancer is probably the most dreaded disease in both men and women and also major
health problem worldwide. Despite its high prevalence, the exact molecular mechanisms of …
health problem worldwide. Despite its high prevalence, the exact molecular mechanisms of …
[HTML][HTML] Thymoquinone as a potential adjuvant therapy for cancer treatment: evidence from preclinical studies
AGM Mostofa, MK Hossain, D Basak… - Frontiers in …, 2017 - frontiersin.org
Thymoquinone (TQ), the main bioactive component of Nigella sativa, has been found to
exhibit anticancer effects in numerous preclinical studies. Due to its multitargeting nature, TQ …
exhibit anticancer effects in numerous preclinical studies. Due to its multitargeting nature, TQ …
[HTML][HTML] Interactions in cancer treatment considering cancer therapy, concomitant medications, food, herbal medicine and other supplements
CPJG Wolf, T Rachow, T Ernst, A Hochhaus… - Journal of Cancer …, 2022 - Springer
Purpose The aim of our study was to analyse the frequency and severity of different types of
potential interactions in oncological outpatients' therapy. Therefore, medications, food and …
potential interactions in oncological outpatients' therapy. Therefore, medications, food and …
[HTML][HTML] A phase I clinical trial to evaluate the safety of thymoquinone-rich black cumin oil (BlaQmax®) on healthy subjects: Randomized, double-blinded, placebo …
JV Thomas, ME Mohan, P Prabhakaran, B Maliakel… - Toxicology Reports, 2022 - Elsevier
Black cumin or black seed (Nigella sativa L.) is a popular medicinal herb and culinary spice
belonging to Ranunculacea family. Thymoquinone (TQ) is the major active phytoconstituent …
belonging to Ranunculacea family. Thymoquinone (TQ) is the major active phytoconstituent …
[HTML][HTML] Complementary and alternative medicine (CAM) supplements in cancer outpatients: analyses of usage and of interaction risks with cancer treatment
CPJG Wolf, T Rachow, T Ernst, A Hochhaus… - Journal of Cancer …, 2022 - Springer
Purpose The aim of our study was to analyze the use of complementary and alternative
medicine (CAM) supplements, identify possible predictors, and analyze and compile …
medicine (CAM) supplements, identify possible predictors, and analyze and compile …
Potential cytochrome P450-mediated pharmacokinetic interactions between herbs, food, and dietary supplements and cancer treatments
Herbs, food and dietary supplements (HFDS), can interact significantly with anticancer drug
treatments via cytochrome p450 isoforms (CYP) CYP3A4, CYP2D6, CYP1A2, and CYP2C8 …
treatments via cytochrome p450 isoforms (CYP) CYP3A4, CYP2D6, CYP1A2, and CYP2C8 …
[HTML][HTML] Studying the inhibitory effect of quercetin and thymoquinone on human cytochrome P450 enzyme activities
F Elbarbry, A Ung, K Abdelkawy - Pharmacognosy magazine, 2017 - ncbi.nlm.nih.gov
Background: Quercetin (QR) and thymoquinone (TQ) are herbal remedies that are currently
extensively used by the general population to prevent and treat various chronic conditions …
extensively used by the general population to prevent and treat various chronic conditions …