Update on Melasma—part II: treatment

DP Cassiano, ACC Espósito, CN da Silva… - Dermatology and …, 2022 - Springer
Melasma is a prevalent chronic relapsing pigmentary disorder that affects photoexposed
areas, especially in women of childbearing age. Although there is currently no curative …

Efficacy and safety of a novel weekly topical metformin-loaded peel-off mask in the treatment of melasma: a split-face, placebo-controlled study

MHM El-Komy, SW Elnowaihy… - Clinical and …, 2024 - academic.oup.com
Background Melasma is a common condition that affects a patient's quality of life. Metformin
is a cheap, well-tolerated and relatively safe medication that is widely prescribed for the …

An Update on New and Existing Treatments for the Management of Melasma

C Gan, M Rodrigues - American Journal of Clinical Dermatology, 2024 - Springer
Melasma is a chronic, acquired disorder of focal hypermelanosis that carries significant
psychosocial impact and is challenging for both the patient and the treating practitioner to …

Efficacy and safety of metformin for melasma treatment: a systematic review and meta-analysis

P Mongkhon, C Ruengorn, R Awiphan… - Frontiers in …, 2023 - frontiersin.org
Objective: Metformin has recently been demonstrated to have an anti-melanogenic activity.
Nevertheless, clinical evidence of the effectiveness of metformin in melasma is lacking. The …

Innovations in Hyperpigmentation

CN Obeng-Nyarko, KSP Durango… - Dermatologic …, 2024 - derm.theclinics.com
Melasma, post-inflammatory hyperpigmentation (PIH), lichen planus pigmentosus (LPP),
confluent and reticulated papillomatosis of Gougerot and Carteaud (CARP), erythema …

Skin hyperpigmentation index in melasma: A complementary method to classic scoring systems

K Heidemeyer, S Cazzaniga… - Journal of cosmetic …, 2023 - Wiley Online Library
Background Due to relapsing nature of melasma with significant impact on quality of life, an
objective measurement score is warranted, especially to follow‐up the patients with …

Update on melasma management

HOY Li, E Pastukhova… - Advances in …, 2023 - advancesincosmeticsurgery.com
Melasma is a commonly acquired hyperpigmentary disorder that predominately affects
female patients of skin of color, such as Fitzpatrick skin phototypes III–V. Although the …

Topical metformin 30% gel in the treatment of acne vulgaris in women, a split face, placebo‐controlled study

MHM EL‐Komy, NMK Abdo… - Experimental …, 2023 - Wiley Online Library
Acne vulgaris (AV), a widely common disorder, that negatively affects the quality of life.
Metformin is a relatively safe, cheap and well tolerated drug that is widely used in the …

A Systematic Review on Clinical Evidence for Topical Metformin: Old Medication With New Application

K Afshar, S Adibfard, MH Nikbakht… - Health Science …, 2024 - Wiley Online Library
ABSTRACT Background and Aims Metformin is a widely used oral agent for controlling
diabetes mellitus, but it also has other therapeutic benefits for various conditions. In addition …

Comparison of effectiveness and safety of topical 30% metformin versus 4% hydroquinone in the treatment of epidermal melasma

A Hussain, U Shahbaz, E Shaheen, A Ghias… - Journal of Pakistan …, 2024 - jpad.com.pk
Objective To compare the effectiveness and safety of topical 30% metformin versus 4%
hydroquinone in the treatment of epidermal melasma. Methods The study was a randomized …