As nanocarriers (NCs) can improve the solubility of drugs, prevent their degradation by
gastrointestinal (GI) enzymes and promote their transport across the mucus gel layer and …

The past two decades have witnessed a rapid progress in the development of surface
charge‐reversible nanoparticles (NPs) for drug delivery and diagnosis. These NPs are able …

The use of biofluids as a diagnostic tool for chronic health conditions has been gaining
traction in recent years. These fluids, which can be obtained non-invasively (such as urine …

Enzymes and their regulations are employed as indicators for various diseases, including
cancer. To directly analyze the activity of the enzymes within a biological system, enzyme …

We report for the first time the controlled drug release from a nanoscale Zr-based metal–
organic framework (MOF), UiO-66, in the presence of the enzyme alkaline phosphatase …

Currently, specific cancer-responsive fluorogenic probes with activatable imaging and
therapeutic functionalities are in great demand in the accurate diagnostics and efficient …

In this study PEG-free and zeta potential changing lipid-based nanocarriers providing
enhanced cellular uptake were developed. Nanostructured lipid carriers (NLC), consisting of …

Nanodrug delivery system has a great application in the treatment of solid tumors by virtue of
EPR effect, though its success in clinics is still limited by its poor extravasation, small …

The excellent stability and economic benefits of nanozymes have piqued researchers'
interest as they represent a type of nanomaterials with enzyme-catalyzed capabilities …

Heterocycles are a class of compounds that have been found to be potent inhibitors of
alkaline phosphatase (AP), an enzyme that plays a critical role in various physiological …