Cardiovascular risk in rheumatoid arthritis: recent advances in the understanding of the pivotal role of inflammation, risk predictors and the impact of treatment

E Choy, K Ganeshalingam, AG Semb… - …, 2014 - academic.oup.com
Risk of cardiovascular (CV) disease is increased among RA patients. High inflammatory
burden associated with RA appears to be a key driver of the increased cardiovascular risk …

Cardiovascular disease in autoimmune rheumatic diseases

I Hollan, PL Meroni, JM Ahearn, JWC Tervaert… - Autoimmunity …, 2013 - Elsevier
Various autoimmune rheumatic diseases (ARDs), including rheumatoid arthritis,
spondyloarthritis, vasculitis and systemic lupus erythematosus, are associated with …

The interplay between inflammation and metabolism in rheumatoid arthritis

MS Chimenti, P Triggianese, P Conigliaro… - Cell death & …, 2015 - nature.com
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by extensive
synovitis resulting in erosions of articular cartilage and marginal bone that lead to joint …

Adipose tissue dysfunction in nascent metabolic syndrome

AA Bremer, I Jialal - Journal of obesity, 2013 - Wiley Online Library
The metabolic syndrome (MetS) confers an increased risk for both type 2 diabetes mellitus
(T2DM) and cardiovascular disease (CVD). Moreover, studies on adipose tissue biology in …

Differential effects of metformin on age related comorbidities in older men with type 2 diabetes

CP Wang, C Lorenzo, SL Habib, B Jo… - Journal of Diabetes and …, 2017 - Elsevier
Aims To identify distinct temporal likelihoods of age-related comorbidity (ARC) diagnoses:
cardiovascular diseases (CVD), cancer, depression, dementia, and frailty-related diseases …

Jean-Charles Preiser

E Gremese, G Ferraccioli - medicine, 2013 - thelancet.com
Tofacitinib for rheumatoid arthritis Page 1 Correspondence 1812 www.thelancet.com Vol 381
May 25, 2013 same chance of getting results as those with BMI <30, since BMI can affect the …

Busting the myth of methotrexate chronic hepatotoxicity

V Di Martino, DW Verhoeven, F Verhoeven… - Nature Reviews …, 2023 - nature.com
Methotrexate is a key component of the treatment of inflammatory rheumatic diseases and
the mainstay of therapy in rheumatoid arthritis. Hepatotoxicity has long been a concern for …

[HTML][HTML] Cardiovascular risk assessment in patients with rheumatoid arthritis: The relevance of clinical, genetic and serological markers

R López-Mejías, S Castañeda… - Autoimmunity …, 2016 - Elsevier
Cardiovascular disease (CV) is the most common cause of premature mortality in patients
with rheumatoid arthritis (RA). This is the result of an accelerated atherosclerotic process …

Increased chemerin and decreased omentin-1 in both adipose tissue and plasma in nascent metabolic syndrome

I Jialal, S Devaraj, H Kaur… - The Journal of …, 2013 - academic.oup.com
Context: Adipose tissue dysregulation causing aberrant adipokine secretion contributes
toward the proinflammatory state of metabolic syndrome (MetS). However, there are scant …

Obesity as a risk and severity factor in rheumatic diseases (autoimmune chronic inflammatory diseases)

E Gremese, B Tolusso, MR Gigante… - Frontiers in …, 2014 - frontiersin.org
The growing body of evidence recognizing the adipose tissue (AT) as an active endocrine
organ secreting bioactive mediators involved in metabolic and inflammatory disorders …