Cells have evolved sophisticated multi-protein complexes that can regulate gene activity at
various steps of the transcription process. Recent advances highlight the role of nuclear …

Dosage compensation is an epigenetic mechanism that normalizes gene expression from
unequal copy numbers of sex chromosomes. Different organisms have evolved alternative …

Little is known about the functional domain architecture of long noncoding RNAs (lncRNAs)
because of a relative paucity of suitable methods to analyze RNA function at a domain level …

Dosage compensation is the crucial process that equalizes gene expression from the X
chromosome between males (XY) and females (XX). In Drosophila, the male-specific lethal …

Like other alpha-herpesviruses, Herpes Simplex Virus Type 1 (HSV-1) possesses the ability
to establish latency in sensory ganglia as a non-integrated, nucleosome-associated …

Dosage compensation in Drosophila increases the transcription of genes on the single X
chromosome in males to equal that of both X chromosomes in females. Site-specific histone …

The genomes of higher eukaryotes are carefully balanced systems of gene expression that
compensate for the different numbers of sex chromosomes in the two sexes by adjusting …

Dosage compensation in male Drosophila relies on the X chromosome–specific recruitment
of a chromatin-modifying machinery, the dosage compensation complex (DCC). The …

X-chromosome dosage compensation in Drosophila requires the male-specific lethal (MSL)
complex, which up-regulates gene expression from the single male X chromosome. Here …

The epigenetic phospho-serine 10 modification of histone H3 has been a puzzle due to its
association with two apparently opposed chromatin states. It is found at elevated levels on …