[HTML][HTML] A global review on short peptides: frontiers and perspectives

V Apostolopoulos, J Bojarska, TT Chai, S Elnagdy… - Molecules, 2021 - mdpi.com
Peptides are fragments of proteins that carry out biological functions. They act as signaling
entities via all domains of life and interfere with protein-protein interactions, which are …

[HTML][HTML] Cyclic dipeptides: The biological and structural landscape with special focus on the anti-cancer proline-based scaffold

J Bojarska, A Mieczkowski, ZM Ziora, M Skwarczynski… - Biomolecules, 2021 - mdpi.com
Cyclic dipeptides, also know as diketopiperazines (DKP), the simplest cyclic forms of
peptides widespread in nature, are unsurpassed in their structural and bio-functional …

Production of porous activated carbons from Caesalpinia ferrea seed pod wastes: Highly efficient removal of captopril from aqueous solutions

FM Kasperiski, EC Lima, CS Umpierres… - Journal of Cleaner …, 2018 - Elsevier
Porous activated carbons (ACs) prepared from a lignocellulosic waste, Caesalpinia ferrea
seed pod wastes (CF) were utilised for removing captopril pharmaceutical from synthetic …

[HTML][HTML] Small molecule angiotensin converting enzyme inhibitors: A medicinal chemistry perspective

W Zheng, E Tian, Z Liu, C Zhou, P Yang… - Frontiers in …, 2022 - frontiersin.org
Angiotensin-converting enzyme (ACE), a zinc metalloprotein, is a central component of the
renin–angiotensin system (RAS). It degrades bradykinin and other vasoactive peptides …

Close-Up Look at Electronic Spectroscopic Signatures of Common Pharmaceuticals in Solution

S Gómez, M Ambrosetti, T Giovannini… - The Journal of Physical …, 2024 - ACS Publications
Simulating electronic properties and spectral signals requires robust computational
approaches that need tuning with the system's peculiarities. In this paper, we test implicit …

[HTML][HTML] Structural and biofunctional insights into the Cyclo (Pro-Pro-Phe-Phe-) Scaffold from experimental and in silico studies: Melanoma and beyond

J Bojarska, M Breza, M Remko, M Czyz… - International Journal of …, 2022 - mdpi.com
Short peptides have great potential as safe and effective anticancer drug leads. Herein, the
influence of short cyclic peptides containing the Pro-Pro-Phe-Phe sequence on patient …

Corrosion inhibition induced by captopril in Hanks' solution on bioresorbable Mg–Zn-(Y, Nd) alloys fabricated by powder metallurgical technology

B Siswayanti, BR Elvira, FP Lestari, A Erryani… - Materials Chemistry and …, 2024 - Elsevier
Mg–Zn alloys containing rare-earth elements (REEs) have been regarded as potential
candidates for bioresorbable stent materials. As implanted in coronary arteries, stents could …

A supramolecular self-assembly of peptide-derived compounds via 1, 5-disubstituted tetrazole-based supramolecular synthons: An experimental and computational …

J Bojarska, M Breza, M Remko, Y Yuan… - Journal of Molecular …, 2023 - Elsevier
The tetrazole moiety is a versatile scaffold in medicinal chemistry due to its specific structure
and essential roles in biosciences. Here, a supramolecular behavior of newly synthesized …

[HTML][HTML] Supramolecular synthon hierarchy in cyclopropyl-containing peptide-derived compounds

J Bojarska, M Breza, M Remko, P Borowiecki… - …, 2022 - pubs.rsc.org
Considering the increasing importance of cyclopropyl-containing peptide-derived
compounds in the pharmaceutical industry, herein, we report the crystal engineering of a …

[HTML][HTML] A Proline-Based Tectons and Supramolecular Synthons for Drug Design 2.0: A Case Study of ACEI

J Bojarska, M Remko, M Breza, I Madura, A Fruziński… - Pharmaceuticals, 2020 - mdpi.com
Proline is a unique, endogenous amino acid, prevalent in proteins and essential for living
organisms. It is appreciated as a tecton for the rational design of new bio-active substances …