Leveraging big data analytics in healthcare enhancement: trends, challenges and opportunities

A Rehman, S Naz, I Razzak - Multimedia Systems, 2022 - Springer
Clinical decisions are more promising and evidence-based, hence, big data analytics to
assist clinical decision-making has been expressed for a variety of clinical fields. Due to the …

Empirical comparison and analysis of web-based cell-penetrating peptide prediction tools

R Su, J Hu, Q Zou, B Manavalan… - Briefings in …, 2020 - academic.oup.com
Cell-penetrating peptides (CPPs) facilitate the delivery of therapeutically relevant molecules,
including DNA, proteins and oligonucleotides, into cells both in vitro and in vivo. This unique …

Predicting diabetes mellitus with machine learning techniques

Q Zou, K Qu, Y Luo, D Yin, Y Ju, H Tang - Frontiers in genetics, 2018 - frontiersin.org
Diabetes mellitus is a chronic disease characterized by hyperglycemia. It may cause many
complications. According to the growing morbidity in recent years, in 2040, the world's …

Feature selection in machine learning: A new perspective

J Cai, J Luo, S Wang, S Yang - Neurocomputing, 2018 - Elsevier
High-dimensional data analysis is a challenge for researchers and engineers in the fields of
machine learning and data mining. Feature selection provides an effective way to solve this …

POSREG: proteomic signature discovered by simultaneously optimizing its reproducibility and generalizability

F Li, Y Zhou, Y Zhang, J Yin, Y Qiu… - Briefings in …, 2022 - academic.oup.com
Mass spectrometry-based proteomic technique has become indispensable in current
exploration of complex and dynamic biological processes. Instrument development has …

MRMD2. 0: a python tool for machine learning with feature ranking and reduction

S He, F Guo, Q Zou - Current Bioinformatics, 2020 - ingentaconnect.com
Aims: The study aims to find a way to reduce the dimensionality of the dataset. Background:
Dimensionality reduction is the key issue of the machine learning process. It does not only …

Deep-AmPEP30: improve short antimicrobial peptides prediction with deep learning

J Yan, P Bhadra, A Li, P Sethiya, L Qin, HK Tai… - … Therapy-Nucleic Acids, 2020 - cell.com
Antimicrobial peptides (AMPs) are a valuable source of antimicrobial agents and a potential
solution to the multi-drug resistance problem. In particular, short-length AMPs have been …

Tumor origin detection with tissue-specific miRNA and DNA methylation markers

W Tang, S Wan, Z Yang, AE Teschendorff… - Bioinformatics, 2018 - academic.oup.com
Motivation A clear identification of the primary site of tumor is of great importance to the next
targeted site-specific treatments and could efficiently improve patient's overall survival. Even …

Performance of machine-learning scoring functions in structure-based virtual screening

M Wójcikowski, PJ Ballester, P Siedlecki - Scientific Reports, 2017 - nature.com
Classical scoring functions have reached a plateau in their performance in virtual screening
and binding affinity prediction. Recently, machine-learning scoring functions trained on …

Multi-categorical deep learning neural network to classify retinal images: A pilot study employing small database

JY Choi, TK Yoo, JG Seo, J Kwak, TT Um, TH Rim - PloS one, 2017 - journals.plos.org
Deep learning emerges as a powerful tool for analyzing medical images. Retinal disease
detection by using computer-aided diagnosis from fundus image has emerged as a new …