Fluctuations in stochastic systems are usually characterized by full counting statistics, which
analyzes the distribution of the number of events taking place in the fixed time interval. In an …

In quantum transport through nanoscale devices, fluctuations arise from various sources: the
discreteness of charge carriers, the statistical nonequilibrium that is required for device …

The rate of product formation is an important measure of the speed of enzyme reactions.
Classical studies of enzyme reactions have been conducted in dilute solutions and under …

Abstract The celebrated Michaelis-Menten (MM) expression provides a fundamental relation
between the rate of enzyme catalysis and substrate concentration. The validity of this …

The distribution of waiting times between successive tunneling events is an already
established method to characterize current fluctuations in mesoscopic systems. Here, I …

Quantum transport of electrons through a molecule is a series of individual electron
tunneling events separated by stochastic waiting time intervals. We study the emergence of …

Recent fluorescence spectroscopy measurements of the turnover time distribution of single-
enzyme turnover kinetics of β-galactosidase provide evidence of Michaelis–Menten kinetics …

Recent studies in single-molecule enzyme kinetics reveal that the turnover statistics of a
single enzyme is governed by the waiting time distribution that decays as mono-exponential …

Classical theories of enzyme inhibition kinetics predict a monotonic decrease in the mean
catalytic activity with the increase in inhibitor concentration. The steady-state result, derived …

Enzyme-to-enzyme variation in the catalytic rate is ubiquitous among single enzymes
created from the same genetic information, which persists over the lifetimes of living cells …