Experimental urinary bladder tumours have been proposed as a useful model for the study
of urinary bladder carcinogenesis, as well as for evaluating new therapeutic strategies …

The administration of chemical carcinogens is one of the most commonly used methods to
induce tumors in several organs in laboratory animals in order to study oncologic diseases …

Bladder cancer (urothelial cancer of the bladder) is the most common malignancy affecting
the urinary system with increasing incidence and mortality. Treatment of bladder cancer has …

The urothelium of the bladder functions as a waterproof barrier between tissue and
outflowing urine. Largely quiescent during homeostasis, this unique epithelium rapidly …

Bladder cancer is one of the most common causes of death in industrialized countries. New
tumor markers and therapeutic approaches are still needed to improve the management of …

Urothelial cell carcinoma (UCC) of the bladder is one of the most common malignancies
worldwide, causing considerable morbidity and mortality. It is unusual among the epithelial …

Mitomycin C (MMC) has shown potent efficacy against a wide spectrum of cancers and is
clinical first choice in superficial bladder tumors. However, intravesical chemotherapy with …

Most of the cancer xenograft models are derived from tumor cell lines, but they do not
sufficiently represent clinical cancer characteristics. Our objective was to develop xenograft …

Mammary cancer is one of the most common cancers, victimizing more than half a million of
women worldwide every year. Despite all the studies in this field, the current therapeutic …

Bladder cancer is highly recurrent following specific transurethral resection and intravesical
chemotherapy, which has prompted continuing efforts to develop novel therapeutic agents …