According to the latest report from the World Health Organization, an estimated 265,000
deaths still occur every year as a direct result of burn injuries. A widespread range of these …

Endothelial cells (ECs) lining all blood vessels are subjected to large mechanical stresses
that regulate their structure and function in health and disease. Here, we review EC …

The way in which a cell migrates is influenced by the physical properties of its surroundings,
in particular the properties of the extracellular matrix. How the physical aspects of the cell's …

Dynamics of epithelial monolayers has recently been interpreted in terms of a jamming or
rigidity transition. How cells control such phase transitions is, however, unknown. Here we …

Blood-contacting surfaces of cardiovascular devices are not biocompatible for creating an
endothelial layer on them. Numerous research studies have mainly sought to modify these …

Preventing infections is one of the main focuses of wound care. The colonisation of wounds
by microorganisms can in fact have negative consequences on the healing process …

The basement membrane (BM) is a thin specialized extracellular matrix that functions as a
cellular anchorage site, a physical barrier and a signaling hub. While the literature on the …

Tissue-engineered skin is ideal for clinical wound repair. Restoration of skin tissue defects
using tissue-engineered skin remains a challenge owing to insufficient vascularisation. In …

Cardiovascular diseases are prevalent worldwide and are the most frequent causes of death
in the United States. Although spending in drug discovery/development has increased, the …

In vivo, cells of the vascular system are subjected to various mechanical stimuli and have
demonstrated the ability to adapt their behavior via mechanotransduction. Recent advances …