RNA‐binding proteins and translation control in angiogenesis

MR Smith, G Costa - The FEBS journal, 2022 - Wiley Online Library
Tissue vascularization through the process of angiogenesis ensures adequate oxygen and
nutrient supply during development and regeneration. The complex morphogenetic events …

Insights into the involvement of circular RNAs in autoimmune diseases

X Zhai, Y Zhang, S Xin, P Cao, J Lu - Frontiers in Immunology, 2021 - frontiersin.org
Circular RNAs (circRNAs) are single-stranded, endogenous, non-coding RNA (ncRNA)
molecules formed by the backsplicing of messenger RNA (mRNA) precursors and have …

Regulated dicing of pre-mir-144 via reshaping of its terminal loop

R Shang, DA Kretov, SI Adamson, T Treiber… - Nucleic acids …, 2022 - academic.oup.com
Although the route to generate microRNAs (miRNAs) is often depicted as a linear series of
sequential and constitutive cleavages, we now appreciate multiple alternative pathways as …

SINEUP long non-coding RNA acts via PTBP1 and HNRNPK to promote translational initiation assemblies

N Toki, H Takahashi, H Sharma… - Nucleic acids …, 2020 - academic.oup.com
SINEUPs are long non-coding RNAs (lncRNAs) that contain a SINE element, and which up-
regulate the translation of target mRNA. They have been studied in a wide range of …

[HTML][HTML] A therapeutically targetable positive feedback loop between lnc-HLX-2-7, HLX, and MYC that promotes group 3 medulloblastoma

K Katsushima, K Joshi, M Yuan, B Romero, M Batish… - Cell Reports, 2024 - cell.com
Recent studies suggest that long non-coding RNAs (lncRNAs) contribute to
medulloblastoma (MB) formation and progression. We have identified an lncRNA, lnc-HLX-2 …

Mapping the Ku interactome using proximity-dependent biotin identification in human cells

S Abbasi, C Schild-Poulter - Journal of proteome research, 2018 - ACS Publications
The Ku heterodimer, composed of Ku70 and Ku80, is best characterized for its role in
repairing double-stranded DNA breaks but is also known to participate in other regulatory …

Identification of whole-cell dsRNA-binding proteins by phase separation

Z Yang, J Zhou, Z Li, J Guo, L Fang, X Xiao, S Xiao - RNA biology, 2024 - Taylor & Francis
Interactions between double-stranded RNA (dsRNA) and proteins play an important role in
cellular homeostasis by regulating the editing, stability, and splicing of intracellular RNA …

hTERT promotes CRC proliferation and migration by recruiting YBX1 to increase NRF2 expression

C Gong, H Yang, S Wang, J Liu, Z Li, Y Hu… - Frontiers in cell and …, 2021 - frontiersin.org
High human telomerase reverse transcriptase (hTERT) expression is related to severe
Colorectal Cancer (CRC) progression and negatively related to CRC patient survival …

NF45 and NF90 regulate mitotic gene expression by competing with Staufen-mediated mRNA decay

S Nourreddine, G Lavoie, J Paradis, KB El Kadhi… - Cell reports, 2020 - cell.com
In human cells, the expression of∼ 1,000 genes is modulated throughout the cell cycle.
Although some of these genes are controlled by specific transcriptional programs, very little …

ILF3 is responsible for hyperlipidemia-induced arteriosclerotic calcification by mediating BMP2 and STAT1 transcription

F Xie, Q Cui, Z Wang, B Liu, W Qiao, N Li… - Journal of Molecular and …, 2021 - Elsevier
Calcification is common in atherosclerotic plaque and can induce vulnerability, which further
leads to myocardial infarction, plaque rupture and stroke. The mechanisms of atherosclerotic …