X Zhai, Y Zhang, S Xin, P Cao, J Lu - Frontiers in Immunology, 2021 - frontiersin.org
Circular RNAs (circRNAs) are single-stranded, endogenous, non-coding RNA (ncRNA) molecules formed by the backsplicing of messenger RNA (mRNA) precursors and have …
R Shang, DA Kretov, SI Adamson, T Treiber… - Nucleic acids …, 2022 - academic.oup.com
Although the route to generate microRNAs (miRNAs) is often depicted as a linear series of sequential and constitutive cleavages, we now appreciate multiple alternative pathways as …
SINEUPs are long non-coding RNAs (lncRNAs) that contain a SINE element, and which up- regulate the translation of target mRNA. They have been studied in a wide range of …
Recent studies suggest that long non-coding RNAs (lncRNAs) contribute to medulloblastoma (MB) formation and progression. We have identified an lncRNA, lnc-HLX-2 …
The Ku heterodimer, composed of Ku70 and Ku80, is best characterized for its role in repairing double-stranded DNA breaks but is also known to participate in other regulatory …
Z Yang, J Zhou, Z Li, J Guo, L Fang, X Xiao, S Xiao - RNA biology, 2024 - Taylor & Francis
Interactions between double-stranded RNA (dsRNA) and proteins play an important role in cellular homeostasis by regulating the editing, stability, and splicing of intracellular RNA …
C Gong, H Yang, S Wang, J Liu, Z Li, Y Hu… - Frontiers in cell and …, 2021 - frontiersin.org
High human telomerase reverse transcriptase (hTERT) expression is related to severe Colorectal Cancer (CRC) progression and negatively related to CRC patient survival …
In human cells, the expression of∼ 1,000 genes is modulated throughout the cell cycle. Although some of these genes are controlled by specific transcriptional programs, very little …
F Xie, Q Cui, Z Wang, B Liu, W Qiao, N Li… - Journal of Molecular and …, 2021 - Elsevier
Calcification is common in atherosclerotic plaque and can induce vulnerability, which further leads to myocardial infarction, plaque rupture and stroke. The mechanisms of atherosclerotic …