Quantification of liver fat content with CT and MRI: state of the art

J Starekova, D Hernando, PJ Pickhardt, SB Reeder - Radiology, 2021 - pubs.rsna.org
Hepatic steatosis is defined as pathologically elevated liver fat content and has many
underlying causes. Nonalcoholic fatty liver disease (NAFLD) is the most common chronic …

Noninvasive assessment of liver disease in patients with nonalcoholic fatty liver disease

L Castera, M Friedrich-Rust, R Loomba - Gastroenterology, 2019 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is estimated to afflict approximately 1 billion
individuals worldwide. In a subset of NAFLD patients, who have the progressive form of …

[PDF][PDF] Diagnosis and treatment of alcohol‐associated liver diseases: 2019 practice guidance from the American Association for the Study of Liver Diseases

DW Crabb, GY Im, G Szabo, JL Mellinger… - Hepatology, 2020 - Wiley Online Library
Alcohol-associated liver disease (ALD) represents a spectrum of liver injury resulting from
alcohol use, ranging from hepatic steatosis to more advanced forms including alcoholic …

The diagnosis and management of nonalcoholic fatty liver disease: practice guidance from the American Association for the Study of Liver Diseases

N Chalasani, Z Younossi, JE Lavine, M Charlton… - Hepatology, 2018 - journals.lww.com
This guidance provides a data‐supported approach to the diagnostic, therapeutic, and
preventive aspects of nonalcoholic fatty liver disease (NAFLD) care. A “Guidance” document …

[PDF][PDF] The ASK1 inhibitor selonsertib in patients with nonalcoholic steatohepatitis: a randomized, phase 2 trial

R Loomba, E Lawitz, PS Mantry, S Jayakumar… - …, 2018 - Wiley Online Library
Inhibition of apoptosis signal–regulating kinase 1, a serine/threonine kinase, leads to
improvement in inflammation and fibrosis in animal models of nonalcoholic steatohepatitis …

[PDF][PDF] Noninvasive, quantitative assessment of liver fat by MRI‐PDFF as an endpoint in NASH trials

C Caussy, SB Reeder, CB Sirlin, R Loomba - Hepatology, 2018 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic liver
disease worldwide, and the progressive form of this condition, nonalcoholic steatohepatitis …

Nonalcoholic fatty liver disease: a systematic review

ME Rinella - Jama, 2015 - jamanetwork.com
Importance Nonalcoholic fatty liver disease and its subtype nonalcoholic steatohepatitis
affect approximately 30% and 5%, respectively, of the US population. In patients with …

[HTML][HTML] NAFLD: a multisystem disease

CD Byrne, G Targher - Journal of hepatology, 2015 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
in Western countries that is predicted to become also the most frequent indication for liver …

[PDF][PDF] Diagnostic modalities for nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, and associated fibrosis

ZM Younossi, R Loomba, QM Anstee, ME Rinella… - …, 2018 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a spectrum comprised of isolated steatosis,
nonalcoholic steatohepatitis (NASH), advanced fibrosis, and cirrhosis. The majority of …

Obesity subtypes, related biomarkers & heterogeneity

LPC Mayoral, GM Andrade, EPC Mayoral… - Indian Journal of …, 2020 - journals.lww.com
Obesity is a serious medical condition worldwide, which needs new approaches and
recognized international consensus in treating diseases leading to morbidity. The aim of this …