Although plasma corticosterone is considered the main glucocorticoid involved in regulation
of stress responses in rodents, the presence of plasma cortisol and whether its level can be …

The neural substrates of insomnia/hyperarousal induced by stress remain unknown. Here,
we show that restraint stress leads to hyperarousal associated with strong activation of …

This study investigated effects of different forms of environmental enrichment on behavioral,
endocrinological, and immunological parameters in male mice. For this purpose, animals of …

Psychological stress delays wound healing and decreases immune/inflammatory responses
required for bacterial clearance. To determine if stress increases the susceptibility to wound …

A key step in host defense is leukocyte recruitment into peripheral tissues following infection
by invasive microorganisms. Leukocyte trafficking through tissues is crucial to effective …

When mice were physically restrained in 50-ml tubes for 24 h, a marked decrease of NK
activity was demonstrated in parallel with the elevation of serum corticosterone levels. The …

Stress is known to cause neuropsychiatric diseases, and it has a detrimental impact on the
function of the immune system. Melatonin (MLT), a pineal gland hormone, exhibits potent …

The circadian clock is a critical regulator of immune function. We recently highlighted a role
for the circadian clock in a mouse model of pulmonary inflammation. The epithelial clock …

Spaceflights are known to induce stress and immune dysregulation. Centrifugation, as
hindlimb unloading, is a good ground based-model to simulate altered gravity which occurs …

Immune system is sensitive to stress. Spleen is the largest peripheral immune organ
innervated with sympathetic nerves and controlled by adrenomedullary system in the body …