The eye is a metabolically active structure, constantly exposed to solar radiations making its
structure vulnerable to the high burden of reactive oxygen species (ROS), presenting many …

Melatonin influences insulin secretion both in vivo and in vitro.(i) The effects are MT1‐and
MT2‐receptor‐mediated.(ii) They are specific, high‐affinity, pertussis‐toxin‐sensitive, Gi …

Diabetes mellitus (DM) and diabetes-related complications are amongst the leading causes
of mortality worldwide. The international diabetes federation (IDF) has estimated 592 million …

Melatonin, a pleiotropic hormone, has many regulatory effects on the circadian and
seasonal rhythms, sleep and body immune system. It is used in the treatment of blind …

Cardiomyopathy and pancreatic injury are health issues associated with type 2 diabetes
mellitus (T2DM) and are characterized by elevated oxidative stress, inflammation and …

An elevated oxidative status in the aging organism may be involved in the development of
non‐insulin dependent diabetes mellitus (NIDDM). Melatonin, a potent antioxidant agent, is …

Oxidative stress injury is an important link in the pathogenesis of diabetes, and reducing
oxidative stress damage caused by long-term hyperglycemia is an important diabetic …

A new oxovanadium (IV) chelate [VOL](L: N1-2, 4-dihydroxybenzylidene-N4-2-
hydroxybenzylidene-S-methyl-thiosemicarbazidato) was synthesized and characterized by …

Diabetes is often associated with decreased melatonin level. The aim was to investigate the
effects of different dosage of melatonin on glucose hemostasis, antioxidant ability and …

It is well‐documented that melatonin influences insulin secretion. The effects are mediated
by specific, high‐affinity, pertussis‐toxin‐sensitive, G protein‐coupled membrane receptors …