Staphylococcus aureus is a clinically important pathogen that causes a wide range of
human infections, from minor skin infections to severe tissue infection and sepsis. S. aureus …

Staphylococcus aureus is an opportunistic pathogen and the leading cause of a wide range
of severe clinical infections. The range of diseases reflects the diversity of virulence factors …

Biofilms are matrix‐enclosed microbial aggregates that adhere to a biological or
nonbiological surface. Biofilm formation is a significant problem in the medical, food, and …

The accessory genes of Staphylococcus aureus, in‐cluding those involved in pathogenesis,
are controlled by a complex regulatory network that includes at least four two‐component …

The staphylococcal agr locus encodes a quorum sensing (QS) system that controls the
expression of virulence and other accessory genes by a classical two-component signaling …

The virulence of Staphylococcus aureus is essentially determined by cell wall associated
proteins and secreted toxins that are regulated and expressed according to growth phases …

Understanding the mechanisms implicated in the initial attachment, development, and
maturation of a biofilm phenotype are of tremendous importance for their effect on the …

There are two basic types of bacterial communication systems—those in which the signal is
directed solely at other organisms and those in which the signal is sensed by the producing …

Background: Osteomyelitis is an inflammatory disorder of bone caused by infection leading
to necrosis and destruction. It can affect all ages and involve any bone. Osteomyelitis may …

The expression of Staphylococcus aureus virulence proteins is under the control of RNA III,
a central pleiotropic regulator transcribed from the agr locus. RNA III is activated by at least …