Updates on cytogenetics and molecular genetics of bone and soft tissue tumors:: Ewing sarcoma and peripheral primitive neuroectodermal tumors

AA Sandberg, JA Bridge - Cancer genetics and cytogenetics, 2000 - Elsevier
Cytogenetics of Bone and Soft Tissue Tumors [1]. In view of the remarkable developments in
this field since 1994, both in the cytogenetic and particularly in the molecular genetic …

Promiscuous partnerships in Ewing's sarcoma

S Sankar, SL Lessnick - Cancer genetics, 2011 - Elsevier
Ewing's sarcoma is a highly aggressive bone and soft tissue tumor of children and young
adults. At the molecular genetic level Ewing's sarcoma is characterized by a balanced …

Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks

J Khan, JS Wei, M Ringner, LH Saal, M Ladanyi… - Nature medicine, 2001 - nature.com
The purpose of this study was to develop a method of classifying cancers to specific
diagnostic categories based on their gene expression signatures using artificial neural …

Diagnosis of multiple cancer types by shrunken centroids of gene expression

R Tibshirani, T Hastie… - Proceedings of the …, 2002 - National Acad Sciences
We have devised an approach to cancer class prediction from gene expression profiling,
based on an enhancement of the simple nearest prototype (centroid) classifier. We shrink …

[HTML][HTML] The Ewing family of tumors--a subgroup of small-round-cell tumors defined by specific chimeric transcripts

O Delattre, J Zucman, T Melot, XS Garau… - … England Journal of …, 1994 - Mass Medical Soc
Background Precise diagnosis of small-round-cell tumors is often a challenge to the
pathologist and the clinical oncologist. In Ewing's sarcomas and related peripheral primitive …

MIC2 is a specific marker for Ewing's sarcoma and peripheral primitive neuroectodermal tumors. Evidence for a common histogenesis of Ewing's sarcoma and …

IM Ambros, PF Ambros, S Strehl, H Kovar, H Gadner… - Cancer, 1991 - Wiley Online Library
This study reports on the specific expression of the MIC2 gene, a pseudoautosomal gene
located on the short arms of the X and Y chromosomes, on Ewing's sarcoma (ES) and …

Accurate cancer classification using expressions of very few genes

L Wang, F Chu, W Xie - IEEE/ACM Transactions on …, 2007 - ieeexplore.ieee.org
We aim at finding the smallest set of genes that can ensure highly accurate classification of
cancers from microarray data by using supervised machine learning algorithms. The …

Primary metastatic (stage IV) Ewing tumor: survival analysis of 171 patients from the EICESS studies

M Paulussen, S Ahrens, S Burdach, A Craft… - Annals of oncology, 1998 - Elsevier
Summary Background In the multicenter European Intergroup Cooperative Ewing's Sarcoma
Studies, localized Ewing tumors of bone were treated by combination chemotherapy with …

International randomised controlled trial for the treatment of newly diagnosed EWING sarcoma family of tumours–EURO EWING 2012 Protocol

J Anderton, V Moroz, P Marec-Bérard, N Gaspar… - Trials, 2020 - Springer
Background Although there have been multiple randomised trials in newly diagnosed Ewing
sarcoma family of tumours (ESFT) and these have been conducted over many years and …

Biology of EWS/ETS fusions in Ewing's family tumors

A Arvand, CT Denny - Oncogene, 2001 - nature.com
Tumor-associated chromosomal translocations lead to the formation of chimeric fusions
between the EWS gene and one of five different ETS transcription factors in Ewing's family …