Antimicrobial peptides: from design to clinical application

C Zhang, M Yang - Antibiotics, 2022 - mdpi.com
Infection of multidrug-resistant (MDR) bacteria, such as methicillin-resistant Staphylococcus
aureus (MRSA), carbapenem-resistant Enterobacteriaceae (CRE), and extended-spectrum …

The impact of COVID-19 on multidrug-resistant organisms causing healthcare-associated infections: a narrative review

LS Witt, JR Howard-Anderson, JT Jacob… - JAC-Antimicrobial …, 2023 - academic.oup.com
Abstract Coronavirus disease 2019 (COVID-19) changed healthcare across the world. With
this change came an increase in healthcare-associated infections (HAIs) and a concerning …

Leveraging the COVID-19 pandemic as a natural experiment to assess changes in antibiotic use and antibiotic-resistant E. coli carriage in semi-rural Ecuador

HK Amato, F Loayza, L Salinas, D Paredes, D García… - Scientific reports, 2023 - nature.com
Abstract The coronavirus 2019 (COVID-19) pandemic has had significant impacts on health
systems, population dynamics, public health awareness, and antibiotic stewardship, which …

Changing epidemiology of respiratory tract infection during COVID-19 pandemic

HJ Tang, CC Lai, CM Chao - Antibiotics, 2022 - mdpi.com
The outbreak of COVID-19 has significantly changed the epidemiology of respiratory tract
infection in several ways. The implementation of non-pharmaceutical interventions (NPIs) …

Extended-spectrum β-lactamase-producing gram-negative bacterial infections in severely ill COVID-19 patients admitted in a national referral hospital, Kenya

JM Mutua, JM Njeru, AM Musyoki - Annals of Clinical Microbiology and …, 2023 - Springer
Background Bacterial infections in COVID-19 patients, especially those caused by multidrug-
resistant gram-negative strains, are associated with increased morbidity, hospital stay and …

Secondary Complement Deficiency Impairs Anti-Microbial Immunity to Klebsiella pneumoniae and Staphylococcus aureus During Severe Acute COVID-19

YM Ali, NJ Lynch, P Khatri, IE Bamigbola… - Frontiers in …, 2022 - frontiersin.org
A high incidence of secondary Klebsiella pneumoniae and Staphylococcus aureus infection
were observed in patients with severe COVID-19. The cause of this predisposition to …

Resistome Analysis of Klebsiella pneumoniae Complex from Residential Aged Care Facilities Demonstrates Intra-facility Clonal Spread of Multidrug-Resistant …

JM Blaikie, SA Sapula, NL Siderius, BJ Hart, A Amsalu… - Microorganisms, 2024 - mdpi.com
Antimicrobial-resistant Klebsiella pneumoniae is one of the predominant pathogens in
healthcare settings. However, the prevalence and resistome of this organism within …

Epidemiology of bloodstream infections caused by extended-spectrum cephalosporin-resistant Escherichia coli and Klebsiella pneumoniae in Switzerland, 2015-2022 …

L Damonti, M Gasser, A Kronenberg, N Buetti - Journal of Hospital Infection, 2024 - Elsevier
Background The association between the COVID-19 pandemic and the incidence of
invasive infections caused by multidrug-resistant organisms remains a topic of debate. Aim …

Genetic Analyses of Rare ESBL ST628 Klebsiella pneumoniae Detected during a Protracted Nosocomial Outbreak in the United Kingdom

SME Fordham, F Drobniewski, M Barrow, M Hutchings… - Microorganisms, 2024 - mdpi.com
Klebsiella pneumoniae (K. pneumoniae) cultures from a hospital-wide outbreak in the UK,
which lasted for over 12 months, were sequenced. We sought to sequence and genetically …

The Presence of Virulent and Multidrug-Resistant Clones of Carbapenem-Resistant Klebsiella pneumoniae in Southeastern Brazil

M Borghi, MF Pereira, RP Schuenck - Current Microbiology, 2023 - Springer
The emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) represents an
urgent threat to global public health due to the limited therapeutic options available to …