Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

SE Arnold, Z Arvanitakis… - Nature Reviews …, 2018 - nature.com
Considerable overlap has been identified in the risk factors, comorbidities and putative
pathophysiological mechanisms of Alzheimer disease and related dementias (ADRDs) and …

Glucose transporters in brain in health and disease

H Koepsell - Pflügers Archiv-European Journal of Physiology, 2020 - Springer
Energy demand of neurons in brain that is covered by glucose supply from the blood is
ensured by glucose transporters in capillaries and brain cells. In brain, the facilitative …

Immune modulation of learning, memory, neural plasticity and neurogenesis

R Yirmiya, I Goshen - Brain, behavior, and immunity, 2011 - Elsevier
Over the past two decades it became evident that the immune system plays a central role in
modulating learning, memory and neural plasticity. Under normal quiescent conditions …

Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults

AV Witte, L Kerti, DS Margulies… - Journal of Neuroscience, 2014 - Soc Neuroscience
Dietary habits such as caloric restriction or nutrients that mimic these effects may exert
beneficial effects on brain aging. The plant-derived polyphenol resveratrol has been shown …

Intranasal insulin for Alzheimer's disease

M Hallschmid - CNS drugs, 2021 - Springer
Brain insulin signaling contributes to memory function and might be a viable target in the
prevention and treatment of memory impairments including Alzheimer's disease. This short …

Genomic and epigenomic mechanisms of glucocorticoids in the brain

JD Gray, JF Kogan, J Marrocco… - Nature Reviews …, 2017 - nature.com
Following the discovery of glucocorticoid receptors in the hippocampus and other brain
regions, research has focused on understanding the effects of glucocorticoids in the brain …

[HTML][HTML] The effects of breakfast and breakfast composition on cognition in children and adolescents: a systematic review

K Adolphus, CL Lawton, CL Champ, L Dye - Advances in Nutrition, 2016 - Elsevier
Breakfast is thought to be beneficial for cognitive and academic performance in school
children. However, breakfast is the most frequently skipped meal, especially among …

Astrocyte glycogen and lactate: New insights into learning and memory mechanisms

CM Alberini, E Cruz, G Descalzi, B Bessières, V Gao - Glia, 2018 - Wiley Online Library
Memory, the ability to retain learned information, is necessary for survival. Thus far,
molecular and cellular investigations of memory formation and storage have mainly focused …

Lactate produced by glycogenolysis in astrocytes regulates memory processing

LA Newman, DL Korol, PE Gold - PloS one, 2011 - journals.plos.org
When administered either systemically or centrally, glucose is a potent enhancer of memory
processes. Measures of glucose levels in extracellular fluid in the rat hippocampus during …

The physiology of willpower: Linking blood glucose to self-control

MT Gailliot, RF Baumeister - Personality and social …, 2007 - journals.sagepub.com
Past research indicates that self-control relies on some sort of limited energy source. This
review suggests that blood glucose is one important part of the energy source of self-control …